ZHX1 and SUMO2

Number of citations of the paper that reports this interaction (PubMedID 16524884)
197

Data Source:
BioGRID (two hybrid)

		ZHX1	SUMO2
Description		zinc fingers and homeoboxes 1	small ubiquitin like modifier 2
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm PML Body
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding Protein Heterodimerization Activity	Transcription Corepressor Binding RNA Binding Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Protein Sumoylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways			Vitamin D (calciferol) metabolism SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS			Gamma glutamyl transferase levels ( 29403010)
Interacting Genes		53 interacting genes: AKR1C3 AKT1 ATXN1 BARD1 BCL2L1 BHLHE40 BID CHD3 CREB1 CREBBP CSNK2A1 DDX39B DLST DYNLL1 EFNA2 ELL GADD45A GNG11 GSK3B HSPE1 IDH1 LAMA4 LYAR MPHOSPH6 NACA NFYA PAFAH1B3 PEX14 PIAS4 PIGC PNP PRPF40A PSMD11 SAT1 SERPINB9 SUMO1 SUMO2 TAL1 TALDO1 TARDBP TERF1 TNFRSF10C TOLLIP TP53 UBC UTP3 VIM WDR33 ZHX2 ZHX3 ZMYND11 ZNF33B ZYX	179 interacting genes: ABRAXAS1 AHNAK ALAS1 ANAPC2 ANXA1 ATF7IP ATRX ATXN7 BABAM2 BAD BAZ1A BAZ1B BLM BRCC3 C18orf25 CAD CARS1 CCNE2 CENPC CHAF1A CHAF1B CHAMP1 CHD3 CHD4 CMTM6 CSNK2B CTNND1 CUL3 CUX1 DAXX DCD DDX17 DDX21 DDX3X DNM1L EEF1A1 EEF1G EGLN3 EME1 ENO1 EP300 ERCC4 EXOSC10 EXOSC9 FOS GATAD2B HDAC1 HDAC2 HDAC4 HDAC9 HIPK2 HNRNPF HNRNPH1 HNRNPK HOMEZ HP1BP3 HSF2 HSP90AB1 HSPA1A HSPA8 HSPA9 IPO5 JUN KALRN KDM1A KIF18B LAS1L LEF1 MAF1 MAST2 MDC1 MDN1 MKI67 MRE11 MSH2 MSX1 MTA1 MTA2 MUS81 MYB NBN NFE2L2 NOL9 NOP2 NUMA1 PARN PELP1 PFKM PHF5A PHF8 PIAS1 PIAS2 PIAS3 PIAS4 PML POGZ PRKDC RAD50 RAD51 RAD54L2 RANBP2 RANGAP1 RBBP4 RBBP7 RCOR1 RCOR2 RCOR3 RNF111 RNF168 RNF216 RNF4 RNF8 RPL3 RPL4 RUVBL1 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SIMC1 SLC22A2 SLX4IP SMCHD1 SOBP SOX10 SOX6 SP100 SSRP1 SUPT16H TDG TDP2 TEAD3 TEX10 TMPO TNIP1 TOP2A TOP2B TOPORS TP53BP1 TP53BP2 TPR TRAF1 TRIM26 TRIM28 TRIM63 TRIML2 TUBA1B TUBB TUBB4B TUBB6 UBA2 UBE2I USP11 USP25 USP28 USP7 USPL1 VIM WRN XRCC5 XRCC6 ZBED1 ZBTB2 ZBTB25 ZBTB33 ZCCHC12 ZCCHC7 ZHX1 ZMAT3 ZMYM3 ZMYM4 ZMYM5 ZNF451 ZNF496
Entrez ID		11244	6613
HPRD ID		10379	04332
Ensembl ID		ENSG00000165156	ENSG00000188612
Uniprot IDs		A0A024R9F1 Q9UKY1	A0A024R8S3 P61956
PDB IDs		2ECB 2GHF 2LY9 3NAR	1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2N1W 2N9E 2RPQ 3UIN 3UIO 3ZO5 4BKG 4NPN 5D2M 5ELU 5EQL 5GHB 5GHC
Enriched GO Terms of Interacting Partners?
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