WBP4 and SF3B3

Number of citations of the paper that reports this interaction (PubMedID 16055720)
81

Data Source:
BioGRID (pull down)

		WBP4	SF3B3
Description		WW domain binding protein 4	splicing factor 3b subunit 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs			Quercetin
Diseases
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		44 interacting genes: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		11193	23450
HPRD ID		16086	12027
Ensembl ID		ENSG00000120688	ENSG00000189091
Uniprot IDs		O75554	A8K6V3 Q15393
PDB IDs		2DK1 2JXW 5O9Z 6AHD	5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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