WBP4 and FUS

Number of citations of the paper that reports this interaction (PubMedID 16055720)
81

Data Source:
BioGRID (pull down)

		WBP4	FUS
Description		WW domain binding protein 4	FUS RNA binding protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Polysome Perikaryon Dendritic Spine Head Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Estrogen Receptor Binding Myosin V Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding Metal Ion Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II RNA Splicing Regulation Of RNA Splicing MRNA Stabilization Protein Homooligomerization Cellular Response To Calcium Ion Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Myxoid liposarcoma
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)
Interacting Genes		44 interacting genes: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	45 interacting genes: AKT1 ARID1A ATXN1L CTNNB1 ESRRA EWSR1 GRIN1 GRIN2D IL7R ILF3 KHDRBS3 MAX MDH1 NKD2 NUPR1 POLR2A PRMT1 PSMB7 PTBP1 RBMX RELA RXRA SAFB2 SF1 SFPQ SMARCB1 SMARCC1 SMARCC2 SMARCD1 SPI1 SRRM1 SRSF10 SRSF2 SRSF4 SRSF9 SS18 SUV39H1 TARDBP TDRD3 THRA TNIP1 UBQLN2 WBP4 YBX1 ZMYM2
Entrez ID		11193	2521
HPRD ID		16086	00660
Ensembl ID		ENSG00000120688	ENSG00000089280
Uniprot IDs		O75554	P35637 Q13344 Q6IBQ5
PDB IDs		2DK1 2JXW 5O9Z 6AHD	2LA6 2LCW 4FDD 4FQ3 5W3N 5XRR 5XSG 5YVG 5YVH 5YVI 6BWZ 6BXV 6BZP 6G99 6GBM 6KJ1 6KJ2 6KJ3 6KJ4
Enriched GO Terms of Interacting Partners?
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