SDCBP2 and GABRA3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SDCBP2	GABRA3
Description		syndecan binding protein 2	gamma-aminobutyric acid type A receptor subunit alpha3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Plasma Membrane Nuclear Speck Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Membrane Chloride Channel Complex Neuron Projection Synapse Postsynapse GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane GABA-A Receptor Complex
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	GABA-A Receptor Activity Inhibitory Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Protein Binding Benzodiazepine Receptor Activity GABA-gated Chloride Ion Channel Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Nervous System Development Cell Proliferation Intracellular Signal Transduction Intracellular Transport	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Chloride Transmembrane Transport
Pathways			GABA receptor activation GABA receptor activation
Drugs			Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Butalbital Topiramate Etomidate Talbutal Talbutal Pentobarbital Pentobarbital Olanzapine Clobazam Meprobamate Meprobamate Eszopiclone Eszopiclone Alprazolam Secobarbital Zolpidem Metharbital Metharbital Chlordiazepoxide Amoxapine Adinazolam Thiopental Clorazepate Acamprosate Midazolam Flurazepam Isoflurane Primidone Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Methylphenobarbital Triazolam Triazolam Ethanol Methoxyflurane Ergoloid mesylate Clonazepam Methyprylon Halothane Desflurane Zopiclone Flumazenil Estazolam Estazolam Sevoflurane Amobarbital Aprobarbital Butethal Heptabarbital Hexobarbital Glutethimide Barbital Barbituric acid derivative Flunitrazepam Bromazepam Clotiazepam Fludiazepam Prazepam Prazepam Quazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Pagoclone Ganaxolone Adipiplon Stiripentol Etizolam Thiocolchicoside Lormetazepam
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		44 interacting genes: ADAP1 ARF4 BEND7 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR MED4 NFASC NKAPD1 NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 RPL22 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 TRAF1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2	3 interacting genes: SDCBP2 UBQLN1 UGT2B7
Entrez ID		27111	2556
HPRD ID		18032	02375
Ensembl ID		ENSG00000125775	ENSG00000011677
Uniprot IDs		Q9H190	P34903
PDB IDs
Enriched GO Terms of Interacting Partners?
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