SDCBP2 and SEC23A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SDCBP2	SEC23A
Description		syndecan binding protein 2	Sec23 homolog A, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Plasma Membrane Nuclear Speck Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Extrinsic Component Of Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Nervous System Development Cell Proliferation Intracellular Signal Transduction Intracellular Transport	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of GTPase Activity COPII Vesicle Coating Protein Localization To Plasma Membrane Cargo Loading Into COPII-coated Vesicle
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases			Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS		Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)	Metabolite levels ( 23823483) Vitamin D levels ( 29343764)
Interacting Genes		44 interacting genes: ADAP1 ARF4 BEND7 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR MED4 NFASC NKAPD1 NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 RPL22 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 TRAF1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2	11 interacting genes: CDK16 CDK18 DCTN1 GLRA2 MIA2 MIA3 NDRG1 SDCBP2 SEC16A SEC24B SEC24C
Entrez ID		27111	10484
HPRD ID		18032	06714
Ensembl ID		ENSG00000125775	ENSG00000100934
Uniprot IDs		Q9H190	Q15436
PDB IDs			2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX 5KYN 5KYU 5KYW 5KYX 5KYY 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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