VTI1B and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VTI1B	SYNE4
Description		vesicle transport through interaction with t-SNAREs 1B	spectrin repeat containing nuclear envelope family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Platelet Alpha Granule Lumen SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity	Protein Binding
	Biological Process	Platelet Degranulation Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Platelet degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		13 interacting genes: CLINT1 CREB3 GOLGB1 KRTAP10-7 LDLRAD1 LMNA PTPN5 STX4 STX7 STX8 SYNE4 TNK2 TRIM59	51 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250
Entrez ID		10490	163183
HPRD ID		04440	08776
Ensembl ID		ENSG00000100568	ENSG00000181392
Uniprot IDs		Q9UEU0	Q8N205
PDB IDs		2V8S
Enriched GO Terms of Interacting Partners?
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