VTI1B and TRIM59

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VTI1B	TRIM59
Description		vesicle transport through interaction with t-SNAREs 1B	tripartite motif containing 59
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Platelet Alpha Granule Lumen SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity	Protein Binding Zinc Ion Binding
	Biological Process	Platelet Degranulation Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane	Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response
Pathways		Platelet degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Intrinsic epigenetic age acceleration ( 29374233) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		13 interacting genes: CLINT1 CREB3 GOLGB1 KRTAP10-7 LDLRAD1 LMNA PTPN5 STX4 STX7 STX8 SYNE4 TNK2 TRIM59	9 interacting genes: ECSIT ESR1 ESR2 NRM OTOL1 PPM1L RHOU VTI1B ZDHHC22
Entrez ID		10490	286827
HPRD ID		04440	15568
Ensembl ID		ENSG00000100568	ENSG00000213186
Uniprot IDs		Q9UEU0	Q8IWR1
PDB IDs		2V8S
Enriched GO Terms of Interacting Partners?
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