TRIM38 and EIF1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM38	EIF1B
Description		tripartite motif containing 38	eukaryotic translation initiation factor 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Cellular_component Eukaryotic 43S Preinitiation Complex
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity	RNA Binding Translation Initiation Factor Activity Ribosomal Small Subunit Binding
	Biological Process	Regulation Of Interferon-beta Production Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Defense Response To Virus Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Protein K48-linked Ubiquitination	Translational Initiation Regulation Of Translational Initiation
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cardiac hypertrophy ( 21348951) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730)
Interacting Genes		21 interacting genes: ATXN1 EIF1B GMCL1 GORASP2 HSPA1A HSPA2 HSPA8 RFC5 RIPK1 SDCBP STXBP1 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U	4 interacting genes: ATXN1 DVL2 PEX19 TRIM38
Entrez ID		10475	10289
HPRD ID		15555	17032
Ensembl ID		ENSG00000112343	ENSG00000114784
Uniprot IDs		A0A024QZY4 O00635	O60739 Q6FG85
PDB IDs
Enriched GO Terms of Interacting Partners?
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