EIF1B and TRIM38

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EIF1B	TRIM38
Description		eukaryotic translation initiation factor 1B	tripartite motif containing 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Eukaryotic 43S Preinitiation Complex	Cellular_component Cytosol
	Molecular Function	RNA Binding Translation Initiation Factor Activity Ribosomal Small Subunit Binding	Protein Binding Zinc Ion Binding Transferase Activity
	Biological Process	Translational Initiation Regulation Of Translational Initiation	Regulation Of Interferon-beta Production Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Defense Response To Virus Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Protein K48-linked Ubiquitination
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Cardiac hypertrophy ( 21348951) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730)
Interacting Genes		4 interacting genes: ATXN1 DVL2 PEX19 TRIM38	21 interacting genes: ATXN1 EIF1B GMCL1 GORASP2 HSPA1A HSPA2 HSPA8 RFC5 RIPK1 SDCBP STXBP1 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U
Entrez ID		10289	10475
HPRD ID		17032	15555
Ensembl ID		ENSG00000114784	ENSG00000112343
Uniprot IDs		O60739 Q6FG85	A0A024QZY4 O00635
PDB IDs
Enriched GO Terms of Interacting Partners?
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