C1D and PCBD2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		C1D	PCBD2
Description		C1D nuclear receptor corepressor	pterin-4 alpha-carbinolamine dehydratase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Transcriptional Repressor Complex	Cellular_component Nucleus
	Molecular Function	DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Binding	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Maturation Of 5.8S RRNA RRNA Processing Apoptotic Process Negative Regulation Of Transcription, DNA-templated	Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Familial lung adenocarcinoma ( 29924316) Male-pattern baldness ( 27182965) Obstetric antiphospholipid syndrome ( 28424481) Restless legs syndrome ( 29029846) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)	Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)
Interacting Genes		12 interacting genes: APP IL23R MOGS NCOR1 NCOR2 NR1D1 PCBD2 PRKDC SASH1 THRA THRB TSNAX	33 interacting genes: AATF APP ASCC2 BRF1 C1D CDC5L CENPK CHAF1A F2RL1 FBXO7 GTF2E1 HES4 IRF2BP1 KCNIP3 MAGEA11 MED21 MED30 MED4 MED7 MET PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3
Entrez ID		10438	84105
HPRD ID		07382	17824
Ensembl ID		ENSG00000197223	ENSG00000132570
Uniprot IDs		Q13901	Q9H0N5
PDB IDs			4C45
Enriched GO Terms of Interacting Partners?
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