NDC80 and SGF29

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NDC80	SGF29
Description		NDC80 kinetochore complex component	SAGA complex associated factor 29
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Cell Nucleus Nucleoplasm Centrosome Cytosol Membrane Ndc80 Complex	SAGA Complex Ada2/Gcn5/Ada3 Transcription Activator Complex SAGA-type Complex
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Coregulator Activity Protein Binding Enzyme Binding Methylated Histone Binding Protein N-terminus Binding
	Biological Process	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Organization Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Protein Localization To Kinetochore	Histone Acetylation Histone H3 Acetylation RNA Polymerase II Preinitiation Complex Assembly Establishment Of Protein Localization To Chromatin
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	HATs acetylate histones
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Interacting Genes		46 interacting genes: AMOTL2 ATF4 ATP5PO AURKA AURKB BLOC1S6 CALCOCO1 CCHCR1 CCNH CCNK CENPH CKAP5 HAUS1 HGS IFT20 INPP1 KLC3 KLHL12 KRT6B MAD1L1 MAD2L1 MFAP1 MIS12 NDE1 NDEL1 NEK2 NUF2 PCM1 PFDN1 PSMC2 RB1 RUFY4 SFR1 SGF29 SKA1 SMC1A SPC25 STX11 TFIP11 TNIP1 TOM1L1 TP53BP2 TXLNA USHBP1 WASHC3 ZWINT	11 interacting genes: CCDC102B CCDC158 CLHC1 H3-4 KRT13 KRT15 LNX1 MED4 NDC80 RINT1 TADA3
Entrez ID		10403	112869
HPRD ID		06277	13996
Ensembl ID		ENSG00000080986	ENSG00000176476
Uniprot IDs		A8K031 O14777	Q96ES7
PDB IDs		2IGP 2VE7 3IZ0	3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M
Enriched GO Terms of Interacting Partners?
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