WDR77 and SIRT7

Number of citations of the paper that reports this interaction (PubMedID 30282801)
0

Data Source:
BioGRID (pull down, enzymatic study)

		WDR77	SIRT7
Description		WD repeat domain 77	sirtuin 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome	Chromatin Nucleus Nucleoplasm Nuclear Telomeric Heterochromatin Nucleolus Nucleolus Organizer Region Cytoplasm Site Of Double-strand Break
	Molecular Function	Protein Binding Methyl-CpG Binding Nuclear Receptor Transcription Coactivator Activity	Chromatin Binding Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Deacetylase Activity NAD-dependent Protein Deacetylase Activity Protein-succinyllysine Desuccinylase Activity Metal Ion Binding Protein-glutaryllysine Deglutarylase Activity NAD+ Binding NAD-dependent Histone Deacetylase Activity (H3-K18 Specific)
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Regulation Of Gluconeogenesis DNA Repair Regulation Of DNA Repair Protein Deacetylation Cellular Response To DNA Damage Stimulus Positive Regulation Of Transcription Involved In Exit From Mitosis Synapsis RRNA Transcription Negative Regulation Of Transposition Regulation Of Mitochondrion Organization Histone Modification Negative Regulation Of Protein Ubiquitination Peptidyl-lysine Desuccinylation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Export From Nucleus Protein Deglutarylation Peptidyl-lysine Deglutarylation Histone H3 Deacetylation Histone H4 Deacetylation Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Histone Glutamine Methylation Positive Regulation Of RRNA Processing Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS
Interacting Genes		44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PITRM1 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207	9 interacting genes: APP DDB1 H2AC20 H2BC21 H3C1 H4C1 MAGED1 USP7 WDR77
Entrez ID		79084	51547
HPRD ID		14387	12094
Ensembl ID		ENSG00000116455	ENSG00000187531
Uniprot IDs		A0A024R0H7 Q9BQA1	Q9NRC8
PDB IDs		4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S	5IQZ 6G0S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?