CDK3 and CCNC

Number of citations of the paper that reports this interaction (PubMedID 15084261)
78

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CDK3	CCNC
Description		cyclin dependent kinase 3	cyclin C
Image
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Mediator Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II
Pathways			PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Erectile dysfunction ( 30297428)
Interacting Genes		18 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCNE1 CCNE2 CDC37 CDKN1A CDKN1B CDKN3 E2F1 E2F2 E2F3 KIR3DL1 NEDD4L PPARA RB1	32 interacting genes: CCNH CDK3 CDK8 CRX DYDC1 ERCC3 ESR1 ESR2 FOXP2 GLYR1 GOLGA2 GPC4 HSPB1 KRT13 KRT15 KRT31 LZTS2 MBIP MCM2 MED8 MEOX2 MGST3 NEFL NMNAT1 PBXIP1 PNMA5 PUF60 RB1 TADA3 TP63 TRIM39 ZNF18
Entrez ID		1018	892
HPRD ID		00446	00456
Ensembl ID		ENSG00000250506	ENSG00000112237
Uniprot IDs		Q00526	P24863 Q7Z4L3
PDB IDs		1LFN	3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2
Enriched GO Terms of Interacting Partners?
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