CCNC and GPC4

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		CCNC	GPC4
Description		cyclin C	glypican 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex	Extracellular Region Nucleus Golgi Lumen Plasma Membrane External Side Of Plasma Membrane Cell Surface Lysosomal Lumen Synapse Collagen-containing Extracellular Matrix Extracellular Exosome Glutamatergic Synapse Anchored Component Of Presynaptic Membrane
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Regulation Of Signal Transduction Cell Migration Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Synaptic Membrane Adhesion Regulation Of Protein Localization To Membrane Regulation Of Presynapse Assembly
Pathways		PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport
Drugs
Diseases
GWAS		Erectile dysfunction ( 30297428)
Interacting Genes		32 interacting genes: CCNH CDK3 CDK8 CRX DYDC1 ERCC3 ESR1 ESR2 FOXP2 GLYR1 GOLGA2 GPC4 HSPB1 KRT13 KRT15 KRT31 LZTS2 MBIP MCM2 MED8 MEOX2 MGST3 NEFL NMNAT1 PBXIP1 PNMA5 PUF60 RB1 TADA3 TP63 TRIM39 ZNF18	9 interacting genes: ABHD17A ACP5 AKAP9 CCNC COL18A1 FGF2 PTEN PTPRD PTPRF
Entrez ID		892	2239
HPRD ID		00456	02160
Ensembl ID		ENSG00000112237	ENSG00000076716
Uniprot IDs		P24863 Q7Z4L3	O75487
PDB IDs		3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?