CCNC and PBXIP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCNC	PBXIP1
Description		cyclin C	PBX homeobox interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex	Nucleus Cytosol Microtubule Membrane
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Transcription Corepressor Activity Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II	Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Erectile dysfunction ( 30297428)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		32 interacting genes: CCNH CDK3 CDK8 CRX DYDC1 ERCC3 ESR1 ESR2 FOXP2 GLYR1 GOLGA2 GPC4 HSPB1 KRT13 KRT15 KRT31 LZTS2 MBIP MCM2 MED8 MEOX2 MGST3 NEFL NMNAT1 PBXIP1 PNMA5 PUF60 RB1 TADA3 TP63 TRIM39 ZNF18	22 interacting genes: BRPF1 CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GMCL1 GRB2 MDFI MDM2 MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3
Entrez ID		892	57326
HPRD ID		00456	17823
Ensembl ID		ENSG00000112237	ENSG00000163346
Uniprot IDs		P24863 Q7Z4L3	B4E0K4 Q96AQ6
PDB IDs		3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2
Enriched GO Terms of Interacting Partners?
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