GIT2 and SAFB2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GIT2	SAFB2
Gene Name		G protein-coupled receptor kinase interacting ArfGAP 2	scaffold attachment factor B2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	Nucleotide Binding DNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Behavioral Response To Pain	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Metabolic syndrome ( 20694148) Metabolite levels (MHPG) ( 23319000)	vWF and FVIII levels ( 21810271)
Protein-Protein Interactions		44 interactors: ACTG1 ACTN1 ADRBK1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	8 interactors: CHGB ESR1 FNTA FUS GIT2 SAFB SORBS3 ZSCAN18
Entrez ID		9815	9667
HPRD ID		09779	06424
Ensembl ID		ENSG00000139436	ENSG00000130254
Uniprot IDs		F8VXI9 Q14161 Q6FI58	Q14151
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Ephrin Receptor Signaling Pathway Innate Immune Response Response To External Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Signal Transduction Immune System Process Immune Response Regulation Of Immune System Process Cell Death Regulation Of Metabolic Process Death Positive Regulation Of Immune Response Defense Response Signal Transduction Regulation Of Immune Response Immune Response-regulating Signaling Pathway Adherens Junction Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Immune System Process Focal Adhesion Assembly Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-cell Junction Organization Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Signaling Regulation Of Kinase Activity Cellular Component Assembly Cell Communication Regulation Of Phosphorylation Adherens Junction Assembly Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Cell Development Cell-substrate Junction Assembly Activation Of MAPK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Stress Activation Of Innate Immune Response Cell Surface Receptor Signaling Pathway	Intracellular Estrogen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Tubulin Deacetylation Prostate Epithelial Cord Elongation Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Farnesylation Hormone Metabolic Process Regulation Of Tubulin Deacetylation Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Deacetylase Activity Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Neurotransmitter Receptor Metabolic Process Protein Geranylgeranylation Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Regulation Of Hormone Levels Positive Regulation Of Hydrolase Activity Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Positive Regulation Of Cellular Metabolic Process Vagina Development Uterus Development Protein Prenylation Regulation Of Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Nitric-oxide Synthase Activity Cellular Response To Estradiol Stimulus Prostate Gland Growth Branching Involved In Prostate Gland Morphogenesis Mammary Gland Epithelial Cell Proliferation Female Genitalia Development Behavioral Response To Pain Regulation Of Signaling Positive Regulation Of Monooxygenase Activity Branch Elongation Of An Epithelium Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Deacetylation Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Response To Estrogen Stimulus RNA Metabolic Process Growth
Tagcloud ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?