SAFB2 and CHGB

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAFB2	CHGB
Gene Name		scaffold attachment factor B2	chromogranin B (secretogranin 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Extracellular Region Secretory Granule
	Molecular Function	Nucleotide Binding DNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding	Hormone Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		vWF and FVIII levels ( 21810271)
Protein-Protein Interactions		8 interactors: CHGB ESR1 FNTA FUS GIT2 SAFB SORBS3 ZSCAN18	31 interactors: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 MARK3 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SGK223 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		9667	1114
HPRD ID		06424	07512
Ensembl ID		ENSG00000130254	ENSG00000089199
Uniprot IDs		Q14151	P05060
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Estrogen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Tubulin Deacetylation Prostate Epithelial Cord Elongation Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Farnesylation Hormone Metabolic Process Regulation Of Tubulin Deacetylation Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Deacetylase Activity Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Neurotransmitter Receptor Metabolic Process Protein Geranylgeranylation Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Regulation Of Hormone Levels Positive Regulation Of Hydrolase Activity Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Positive Regulation Of Cellular Metabolic Process Vagina Development Uterus Development Protein Prenylation Regulation Of Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Nitric-oxide Synthase Activity Cellular Response To Estradiol Stimulus Prostate Gland Growth Branching Involved In Prostate Gland Morphogenesis Mammary Gland Epithelial Cell Proliferation Female Genitalia Development Behavioral Response To Pain Regulation Of Signaling Positive Regulation Of Monooxygenase Activity Branch Elongation Of An Epithelium Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Deacetylation Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Response To Estrogen Stimulus RNA Metabolic Process Growth	Regulation Of Cellular Component Organization Regulation Of Growth Regulation Of Developmental Growth Cellular Metabolic Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Regulation Of Metabolic Process Cell Differentiation Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Synaptic Transmission Response To Metal Ion Response To Lipid Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Regulation Of Cell Development Generation Of Neurons Response To Growth Factor Phosphate-containing Compound Metabolic Process Response To Organic Cyclic Compound Protein Homotetramerization Platelet Activation Positive Regulation Of Metabolic Process Response To Stress Metabolic Process Neurogenesis Response To Organic Substance Positive Regulation Of Lamellipodium Assembly Cellular Process Apoptotic Process Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Defense Response Hemostasis DNA-templated Transcription, Initiation Negative Regulation Of Developmental Growth Response To Wounding Long Term Synaptic Depression Programmed Cell Death Regulation Of Neurogenesis Nucleotide-excision Repair Positive Regulation Of Lamellipodium Organization Negative Regulation Of Growth Cell Death Death Cell Development Regulation Of Protein Import Into Nucleus, Translocation Developmental Process Regulation Of Cell Morphogenesis Response To Inorganic Substance
Tagcloud ?			adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von
Tagcloud (Difference) ?			adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von
Tagcloud (Intersection) ?