CHGB and SGK223

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)

		CHGB	SGK223
Gene Name		chromogranin B (secretogranin 1)	homolog of rat pragma of Rnd2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Secretory Granule
	Molecular Function	Hormone Activity Protein Binding	Non-membrane Spanning Protein Tyrosine Kinase Activity ATP Binding
	Biological Process		Peptidyl-tyrosine Phosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 MARK3 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SGK223 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	3 interactors: CHGB PSAP UBE3A
Entrez ID		1114	157285
HPRD ID		07512	19497
Ensembl ID		ENSG00000089199	ENSG00000182319
Uniprot IDs		P05060	Q86YV5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Regulation Of Growth Regulation Of Developmental Growth Cellular Metabolic Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Regulation Of Metabolic Process Cell Differentiation Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Synaptic Transmission Response To Metal Ion Response To Lipid Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Regulation Of Cell Development Generation Of Neurons Response To Growth Factor Phosphate-containing Compound Metabolic Process Response To Organic Cyclic Compound Protein Homotetramerization Platelet Activation Positive Regulation Of Metabolic Process Response To Stress Metabolic Process Neurogenesis Response To Organic Substance Positive Regulation Of Lamellipodium Assembly Cellular Process Apoptotic Process Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Defense Response Hemostasis DNA-templated Transcription, Initiation Negative Regulation Of Developmental Growth Response To Wounding Long Term Synaptic Depression Programmed Cell Death Regulation Of Neurogenesis Nucleotide-excision Repair Positive Regulation Of Lamellipodium Organization Negative Regulation Of Growth Cell Death Death Cell Development Regulation Of Protein Import Into Nucleus, Translocation Developmental Process Regulation Of Cell Morphogenesis Response To Inorganic Substance	Prostate Gland Growth Prostate Gland Development Organ Growth Sperm Entry Developmental Growth Urogenital System Development Growth Gland Development Reproductive Structure Development Reproductive System Development Regulation Of Proteolysis Developmental Process Involved In Reproduction Neuronal Ion Channel Clustering Epithelial Cell Differentiation Involved In Prostate Gland Development Neuron Maturation Single Organism Reproductive Process Protein K48-linked Ubiquitination Reproductive Process Androgen Receptor Signaling Pathway Protein Autoubiquitination Vesicle-mediated Transport Respiratory Gaseous Exchange Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Intracellular Signal Transduction Ovarian Follicle Development Platelet Degranulation Intracellular Steroid Hormone Receptor Signaling Pathway Glycosphingolipid Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Activation Of Cysteine-type Endopeptidase Activity Regulation Of Circadian Rhythm Ovulation Cycle Process Regulation Of Protein Metabolic Process Zymogen Activation Female Gonad Development Nervous System Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Single Fertilization Positive Regulation Of Endopeptidase Activity Glycolipid Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Peptidase Activity Cell Maturation
Tagcloud ?		adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von	abl1 annotates arap1 bcr casl centd2 compensate crk crki crkii directionality dok dok1 dok2 gab2 gtpase gtpases hef1 layered lrrk1 lrrk2 modular nedd9 paralog pleiotropic pragmin rhoa shc1 wise
Tagcloud (Difference) ?		adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von	abl1 annotates arap1 bcr casl centd2 compensate crk crki crkii directionality dok dok1 dok2 gab2 gtpase gtpases hef1 layered lrrk1 lrrk2 modular nedd9 paralog pleiotropic pragmin rhoa shc1 wise
Tagcloud (Intersection) ?