CHGB and MOGS

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHGB	MOGS
Gene Name		chromogranin B (secretogranin 1)	mannosyl-oligosaccharide glucosidase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Secretory Granule	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Hormone Activity Protein Binding	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity
	Biological Process		Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 MARK3 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SGK223 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1	1 interactors: CHGB
Entrez ID		1114	7841
HPRD ID		07512	03214
Ensembl ID		ENSG00000089199	ENSG00000115275
Uniprot IDs		P05060	Q13724 Q58F09
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Regulation Of Growth Regulation Of Developmental Growth Cellular Metabolic Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Regulation Of Metabolic Process Cell Differentiation Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Synaptic Transmission Response To Metal Ion Response To Lipid Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Regulation Of Cell Development Generation Of Neurons Response To Growth Factor Phosphate-containing Compound Metabolic Process Response To Organic Cyclic Compound Protein Homotetramerization Platelet Activation Positive Regulation Of Metabolic Process Response To Stress Metabolic Process Neurogenesis Response To Organic Substance Positive Regulation Of Lamellipodium Assembly Cellular Process Apoptotic Process Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Defense Response Hemostasis DNA-templated Transcription, Initiation Negative Regulation Of Developmental Growth Response To Wounding Long Term Synaptic Depression Programmed Cell Death Regulation Of Neurogenesis Nucleotide-excision Repair Positive Regulation Of Lamellipodium Organization Negative Regulation Of Growth Cell Death Death Cell Development Regulation Of Protein Import Into Nucleus, Translocation Developmental Process Regulation Of Cell Morphogenesis Response To Inorganic Substance
Tagcloud ?		adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von	antiviral april broad compromises diathesis endoplasmic england entry enveloped genetically glucosidase glucosidases glycan hypogammaglobulinemia infectious issue journal manifested mannosyl oligosaccharide paradox phenomenon reticulum sadat spectrum unambiguously validates valuable viruses
Tagcloud (Difference) ?		adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von	antiviral april broad compromises diathesis endoplasmic england entry enveloped genetically glucosidase glucosidases glycan hypogammaglobulinemia infectious issue journal manifested mannosyl oligosaccharide paradox phenomenon reticulum sadat spectrum unambiguously validates valuable viruses
Tagcloud (Intersection) ?