PRPF3 and CTNNBL1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		PRPF3	CTNNBL1
Gene Name		pre-mRNA processing factor 3	catenin, beta like 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane
	Molecular Function	Protein Binding Identical Protein Binding Poly(A) RNA Binding	Protein Binding Enzyme Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Apoptotic Process RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bone mineral density ( 17903296)
Protein-Protein Interactions		24 interactors: BRCA1 CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GTPBP3 NHP2L1 NKAP PCBP1 PPIH PRPF31 PRPF4 RBM39 SART3 SNIP1 TRIM39 U2AF2 USP4 WBP4 ZCCHC10	24 interactors: BUD31 CALCOCO1 CATIP CDC5L CDCA7L CREBZF CWC15 HNRNPK IK LDOC1 LUC7L MED4 MEOX2 NGFRAP1 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP U2SURP WBP11 ZCCHC10
Entrez ID		9129	56259
HPRD ID		07389	10850
Ensembl ID		ENSG00000117360	ENSG00000132792
Uniprot IDs		E7EVD1 O43395	B4DE16 Q8WYA6
PDB IDs		1X4Q	4HM9 4HNM
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Spliceosomal SnRNP Assembly Hematopoietic Stem Cell Proliferation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Ribonucleoprotein Complex Biogenesis Metabolic Process Cochlea Morphogenesis Regulation Of Gene Expression Non-canonical Wnt Signaling Pathway Ribonucleoprotein Complex Assembly Regulation Of Protein Ubiquitination Cochlea Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone Deubiquitination Positive Regulation Of Histone H4-K16 Acetylation Outflow Tract Morphogenesis Positive Regulation Of Histone Modification Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of JUN Kinase Activity Cellular Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of JUN Kinase Activity Stem Cell Proliferation Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction In Response To DNA Damage RNA Biosynthetic Process Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Inner Ear Morphogenesis Negative Regulation Of Protein Ubiquitination Non-canonical Wnt Signaling Pathway Via JNK Cascade	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Regulation Of RNA Metabolic Process Cellular Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Nuclear Speck Organization Spliceosomal Complex Assembly Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecular Complex Assembly Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription, DNA-templated Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Splicing Macromolecule Biosynthetic Process Somite Specification Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Transcription From RNA Polymerase II Promoter Cellular Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Metabolic Process
Tagcloud ?		accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Difference) ?		accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Intersection) ?