PRPF3 and PPIH

Number of citations of the paper that reports this interaction (PMID 16723661)
44

Data Source:
BioGRID (two hybrid, two hybrid)

		PRPF3	PPIH
Gene Name		pre-mRNA processing factor 3	peptidylprolyl isomerase H (cyclophilin H)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Spliceosomal Complex Cytoplasm Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP
	Molecular Function	Protein Binding Identical Protein Binding Poly(A) RNA Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Protein Complex Assembly Positive Regulation Of Viral Genome Replication
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: BRCA1 CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GTPBP3 NHP2L1 NKAP PCBP1 PPIH PRPF31 PRPF4 RBM39 SART3 SNIP1 TRIM39 U2AF2 USP4 WBP4 ZCCHC10	7 interactors: BAG2 N4BP2L2 NHP2L1 PRPF18 PRPF3 PRPF31 PRPF4
Entrez ID		9129	10465
HPRD ID		07389	12084
Ensembl ID		ENSG00000117360	ENSG00000171960
Uniprot IDs		E7EVD1 O43395	O43447 Q6FH36
PDB IDs		1X4Q	1MZW 1QOI
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Spliceosomal SnRNP Assembly Hematopoietic Stem Cell Proliferation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Ribonucleoprotein Complex Biogenesis Metabolic Process Cochlea Morphogenesis Regulation Of Gene Expression Non-canonical Wnt Signaling Pathway Ribonucleoprotein Complex Assembly Regulation Of Protein Ubiquitination Cochlea Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone Deubiquitination Positive Regulation Of Histone H4-K16 Acetylation Outflow Tract Morphogenesis Positive Regulation Of Histone Modification Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of JUN Kinase Activity Cellular Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of JUN Kinase Activity Stem Cell Proliferation Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction In Response To DNA Damage RNA Biosynthetic Process Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Inner Ear Morphogenesis Negative Regulation Of Protein Ubiquitination Non-canonical Wnt Signaling Pathway Via JNK Cascade	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Spliceosomal SnRNP Assembly Gene Expression Ribonucleoprotein Complex Biogenesis Negative Regulation Of Hematopoietic Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Stem Cell Differentiation Cellular Macromolecular Complex Assembly
Tagcloud ?		accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Difference) ?		accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Intersection) ?