AIMP2 and KIAA1377

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		AIMP2	KIAA1377
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	KIAA1377
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Cytoplasm Centrosome Midbody Ciliary Base
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	86 interactors: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM134A FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1D1 YWHAZ ZBED8 ZNF24
Entrez ID		7965	57562
HPRD ID		02915	17212
Ensembl ID		ENSG00000106305	ENSG00000110318
Uniprot IDs		A8MU58 Q13155	Q9P2H0
PDB IDs		4DPG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process	Organelle Organization Cell Cycle Mitotic Cell Cycle Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Cellular Metabolic Process Mitotic Cell Cycle Process Cellular Process Response To Light Stimulus Response To Radiation Triglyceride Catabolic Process Gene Expression Positive Regulation Of Apoptotic Signaling Pathway Organelle Localization Acylglycerol Catabolic Process Endomembrane System Organization Establishment Of Organelle Localization Cell Cycle Process Positive Regulation Of Signal Transduction Peptidyl-lysine Modification Endosome Organization Protein Localization To Organelle Positive Regulation Of Metabolic Process Anatomical Structure Development System Development Regulation Of Signal Transduction Termination Of RNA Polymerase II Transcription Cytoplasmic Transport Programmed Cell Death Chromosome Organization Cell Division Ribosomal Subunit Export From Nucleus Cell Death Regulation Of Signaling Cellular Response To Stimulus Death Histone H3 Acetylation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Ubiquitination Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Response To Abiotic Stimulus Positive Regulation Of Striated Muscle Contraction Cellular Response To Organic Substance RNA Metabolic Process Organ Development Neurotransmitter Uptake
Tagcloud ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Difference) ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Intersection) ?