AIMP2 and BLOC1S4

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		AIMP2	BLOC1S4
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Cytoplasm Cytosol BLOC-1 Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Neuromuscular Process Controlling Balance Membrane Organization Platelet Aggregation
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	7 interactors: AIMP2 BLOC1S1 BLOC1S2 BLOC1S5 BLOC1S6 EPB42 SNAPIN
Entrez ID		7965	55330
HPRD ID		02915	12035
Ensembl ID		ENSG00000106305	ENSG00000186222
Uniprot IDs		A8MU58 Q13155	Q9NUP1
PDB IDs		4DPG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process	Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Axon Cargo Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Microtubule-based Movement Establishment Of Organelle Localization Organelle Localization Synaptic Transmission Microtubule-based Process Neuron Projection Development Cell Differentiation Cell Development Cell-cell Signaling Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Platelet Dense Granule Organization Neuron Differentiation Positive Regulation Of Pigment Cell Differentiation Cell Projection Organization System Development Positive Regulation Of Developmental Pigmentation Multicellular Organismal Development Vesicle-mediated Transport Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Developmental Pigmentation Intracellular Transport Endosomal Transport Generation Of Neurons Neurogenesis Developmental Process Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Membrane Organization Secretory Granule Organization Melanosome Localization Establishment Of Localization In Cell Synaptic Vesicle Exocytosis
Tagcloud ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Difference) ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Intersection) ?