TMSB4X and TAF1D

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TMSB4X	TAF1D
Gene Name		thymosin beta 4, X-linked	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoskeleton Platelet Alpha Granule Lumen	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Microtubule Organizing Center
	Molecular Function	Actin Monomer Binding Protein Binding Poly(A) RNA Binding	DNA Binding Protein Binding
	Biological Process	Platelet Degranulation Actin Filament Organization Blood Coagulation Platelet Activation Sequestering Of Actin Monomers	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation	NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ACTA1 ACTA2 ACTB ACTG1 ALAS1 ANXA7 APLP1 CDKN1A FAM118B GRB7 IGSF21 ILK KRT13 KRT15 KRT31 KRT40 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6	24 interactors: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP NGEF POLB PTN RPL36AL SMARCB1 TAF1A TAF1B TAF1C TMSB4X UBE2D1 UBTF
Entrez ID		7114	79101
HPRD ID		02153	14679
Ensembl ID		ENSG00000205542	ENSG00000166012
Uniprot IDs		A2VCK8 P62328 Q0P5T0	E9PM59 Q9H5J8
PDB IDs		1UY5 3TU5
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Cell Junction Assembly Platelet Aggregation Anatomical Structure Development Response To Stimulus Cell Aging Cell-cell Junction Organization Hemostasis Protein Oligomerization Epithelium Development Adherens Junction Organization Developmental Process Tissue Development Regulation Of Body Fluid Levels Cell-matrix Adhesion Regulation Of Protein Import Into Nucleus Blood Coagulation Cellular Response To Stimulus Platelet Activation Fetal Process Involved In Parturition Regulation Of Protein Localization To Nucleus Cell Adhesion Negative Regulation Of Neural Precursor Cell Proliferation Regulation Of Nucleocytoplasmic Transport Cell-substrate Adhesion Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Signal Transduction Negative Regulation Of Kinase Activity Multicellular Organismal Development Retina Homeostasis Response To Organic Cyclic Compound Single Organismal Cell-cell Adhesion Negative Regulation Of Interleukin-2 Secretion Skeletal Muscle Cell Proliferation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Skeletal Muscle Fiber Adaptation Negative Regulation Of Gene Expression System Development Regulation Of Intracellular Protein Transport Phagocytosis Organ Development Fc Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic Myofibril Assembly Cellular Response To Norepinephrine Stimulus Wound Healing Negative Regulation Of Transferase Activity Regulation Of Protein Transport Protein Complex Assembly	Negative Regulation Of Gene Expression, Epigenetic Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Regulation Of Gene Expression, Epigenetic Chromatin Silencing At RDNA Cellular Macromolecule Biosynthetic Process DNA-templated Transcription, Termination Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription, DNA-templated Biosynthetic Process RNA Biosynthetic Process Chromatin Silencing Gene Expression Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Gene Silencing Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Nitrogen Compound Metabolic Process DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Cell Morphogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Osteoclast Maturation Cellular Process Negative Regulation Of Gene Expression Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Cell Cycle Phase Transition
Tagcloud ?		aldo3 bhlhb2 bnip3 bnip31 cdknla cnn2 cobalt eno2 exerting f10 fdr hk2 itga4 lgals3 mcam mimicry mxil nominal nppb pfkp pkp2 probesets sap30 selenbpl singular u74av2 unsupervised vegfa wise	abundances dephosphorylations dioxide g2 identifies isotope mitosis phosphorylations player polymerases proteomic silac sl1 speculate stoichiometries taf3 taf4 taf7 tafi41 tafs tata tbp tfiid tfiiib tightly titanium transitions tryptic
Tagcloud (Difference) ?		aldo3 bhlhb2 bnip3 bnip31 cdknla cnn2 cobalt eno2 exerting f10 fdr hk2 itga4 lgals3 mcam mimicry mxil nominal nppb pfkp pkp2 probesets sap30 selenbpl singular u74av2 unsupervised vegfa wise	abundances dephosphorylations dioxide g2 identifies isotope mitosis phosphorylations player polymerases proteomic silac sl1 speculate stoichiometries taf3 taf4 taf7 tafi41 tafs tata tbp tfiid tfiiib tightly titanium transitions tryptic
Tagcloud (Intersection) ?