TERF1 and SALL1

Number of citations of the paper that reports this interaction (PMID 11751684)
14

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro)

		TERF1	SALL1
Gene Name		telomeric repeat binding factor (NIMA-interacting) 1	spalt-like transcription factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle	Heterochromatin Nucleus Cytoplasm Chromocenter NuRD Complex
	Molecular Function	DNA Binding Chromatin Binding Double-stranded Telomeric DNA Binding Protein Binding Microtubule Binding DNA Binding, Bending Telomeric DNA Binding Protein Homodimerization Activity Protein Heterodimerization Activity	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Histone Deacetylase Activity Protein Binding Beta-catenin Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Age-dependent Telomere Shortening Telomere Maintenance Via Telomerase Mitotic Nuclear Division Mitotic Spindle Assembly Checkpoint Negative Regulation Of DNA Replication Positive Regulation Of Microtubule Polymerization Telomeric Loop Formation Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Response To Drug Positive Regulation Of Apoptotic Process Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Mitotic Cell Cycle Protein Homooligomerization Cell Division Negative Regulation Of Telomerase Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Kidney Development Neural Tube Closure Ventricular Septum Development Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Transcription, DNA-templated Heart Development Gonad Development Histone Deacetylation Olfactory Nerve Development Olfactory Bulb Interneuron Differentiation Pituitary Gland Development Positive Regulation Of Wnt Signaling Pathway Adrenal Gland Development Inductive Cell-cell Signaling Forelimb Morphogenesis Hindlimb Morphogenesis Outer Ear Morphogenesis Embryonic Digit Morphogenesis Positive Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Digestive Tract Development Limb Development Olfactory Bulb Mitral Cell Layer Development Kidney Epithelium Development Ureteric Bud Invasion Regulation Of Neural Precursor Cell Proliferation
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)	Bone mineral density ( 22504420) C-reactive protein ( 21300955) Optic disc parameters ( 20548946) Weight loss (gastric bypass surgery) ( 23643386)
Protein-Protein Interactions		200 interactors: ACAT2 ACOT7 ACY1 AFAP1L2 AHCY AK1 AKR1A1 ALDOA AMPD2 AMPH ANXA2 ANXA5 APEX1 ARHGDIA ARPP21 ASS1 ATM BCL7B BIN2 BLM BRAF C12orf43 C19orf66 C1orf35 CALD1 CAPNS1 CASP7 CCDC9 CDC6 CEP85 CFL1 CKB CORO1B CPNE3 CRYBB1 CRYM DBN1 DBNL DCX DDX19B DDX21 DDX23 DDX24 DDX39A DLG5 DNAJB1 DNPH1 DPP3 DPYSL3 EEF1D EIF4B ENO2 EPB41L1 EPHX2 EVL FANCD2 FBP1 FBXO4 FEN1 FES FKBP8 GAMT GAPDH GIT1 GNL3L GNMT GSS HCLS1 HDGFRP2 HEXIM1 HEXIM2 HGD HIST1H1A HMGN3 HMGN4 HMOX1 HNMT HOXA3 HSP90AB1 HSPA6 IPO5 JSRP1 KDM1A KEAP1 KIAA1279 KLHDC4 KPNB1 LASP1 LDHA LDHB LRSAM1 LYAR MAP4 MAP7 MAPK12 MAPRE1 MCM2 MDH1 MSN MT1X MVK NAP1L1 NBN NEFL NME1 NME2 NOL12 NOL3 NUDCD2 NUDT14 NUMA1 NXNL1 OCM2 OGFR PA2G4 PACSIN2 PAFAH1B3 PAGE2 PAICS PAK4 PCP4 PEPD PFKP PFN2 PGD PGLS PGM1 PGM2 PINX1 PKM PNMT POT1 PPM1G PRDX1 PRDX6 PRKCB PTMA PTPN5 RBMY1A1 RECQL4 RIC8A RLIM RNF10 RPAP3 RPL19 RTN3 RTN4 SALL1 SARS SBDS SET SH3BP1 SH3GL2 SH3GL3 SIRPD SKP1 SMAD9 SMARCC2 SNCG SOAT1 SP100 SRM SRSF6 STUB1 SULT1C2 SUPT5H SYK TALDO1 TBC1D10A TBCD TBL1X TCIRG1 TERT THG1L TINAG TINF2 TKT TMSB10 TMSB4Y TNKS TNKS2 TNPO2 TOMM34 TPI1 TRIM16 TRIP10 TRMT1 TUBB2A TUBB3 TUBB4B UTP14A WARS WDR4 WFS1 YWHAG ZBTB16 ZC3H18 ZFP36L1 ZHX1 ZNF790	6 interactors: CTNNB1 HDAC1 HDAC2 SUMO1 TERF1 UBE2I
Entrez ID		7013	6299
HPRD ID		02975	03742
Ensembl ID		ENSG00000147601	ENSG00000103449
Uniprot IDs		P54274	Q9NSC2
PDB IDs		1BA5 1H6O 1ITY 1IV6 1W0T 3BQO 3L82
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Organelle Organization Heterocycle Metabolic Process Telomere Maintenance Catabolic Process Small Molecule Metabolic Process Cellular Process Pathogenesis Carbohydrate Biosynthetic Process Monosaccharide Metabolic Process Regulation Of Cellular Component Organization Glucose Metabolic Process Carboxylic Acid Metabolic Process Chromosome Organization Biosynthetic Process Organic Acid Metabolic Process Carbohydrate Catabolic Process Nucleobase-containing Small Molecule Metabolic Process Glycolytic Process Ribose Phosphate Metabolic Process Pyruvate Metabolic Process Telomere Maintenance Via Telomere Lengthening Cellular Component Assembly Protein Complex Assembly Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Gluconeogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Hexose Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomerase Organophosphate Metabolic Process Hexose Biosynthetic Process Cell Cycle Process Mitotic Cell Cycle Metabolic Process Nucleotide Metabolic Process Regulation Of Organelle Organization Nicotinamide Nucleotide Metabolic Process Pentose Biosynthetic Process Glucose 6-phosphate Metabolic Process Response To Organic Substance Regulation Of Telomere Maintenance Regulation Of DNA Replication NADP Metabolic Process Aromatic Compound Catabolic Process	Fungiform Papilla Formation Fungiform Papilla Morphogenesis Fungiform Papilla Development Hair Follicle Placode Formation Tongue Morphogenesis Tongue Development Negative Regulation Of Biosynthetic Process Embryonic Digit Morphogenesis Negative Regulation Of Cellular Metabolic Process Hair Follicle Development Hair Cycle Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Hair Cycle Odontogenesis Of Dentin-containing Tooth Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cell Cycle Positive Regulation Of Receptor Biosynthetic Process Odontogenesis Negative Regulation Of Gene Expression Eyelid Development In Camera-type Eye Epidermal Cell Differentiation Embryonic Limb Morphogenesis Organelle Organization Regulation Of Receptor Biosynthetic Process Positive Regulation Of Protein Complex Assembly Limb Morphogenesis Histone H4 Deacetylation Limb Development Skin Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Sumoylation Histone H3 Deacetylation Epidermis Development Regulation Of Oligodendrocyte Differentiation Regulation Of Cell Cycle Histone H3-K9 Modification Positive Regulation Of Cellular Component Biogenesis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Complex Assembly Camera-type Eye Development Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone Deacetylation Regulation Of Nitrogen Compound Metabolic Process Eye Development Protein Deacetylation Regulation Of Glial Cell Differentiation Regulation Of Signal Transduction ATP-dependent Chromatin Remodeling Circadian Regulation Of Gene Expression
Tagcloud ?		anticancer catalytic cloned compensate division elucidated encoding erosion fusions generally homolog immortality length neoplasms p80 protection repeat repeats repressed ribonucleoprotein telomerase telomere telomeric tep1 terc terf2 tert upregulated withdrawal	bioinformatics chosen continuously exploration exploring fertile governing gpat2 infertile lab list nucleoproteins offspring pld6 progeny proteome proteomics purifying rcor2 renewal shinohara spermatogenesis spermatogonial ssc sscs testes testis undifferentiated uniquely
Tagcloud (Difference) ?		anticancer catalytic cloned compensate division elucidated encoding erosion fusions generally homolog immortality length neoplasms p80 protection repeat repeats repressed ribonucleoprotein telomerase telomere telomeric tep1 terc terf2 tert upregulated withdrawal	bioinformatics chosen continuously exploration exploring fertile governing gpat2 infertile lab list nucleoproteins offspring pld6 progeny proteome proteomics purifying rcor2 renewal shinohara spermatogenesis spermatogonial ssc sscs testes testis undifferentiated uniquely
Tagcloud (Intersection) ?