SPP1 and SSB

Number of citations of the paper that reports this interaction (PMID 22779921)
1

Data Source:
BioGRID (two hybrid)

		SPP1	SSB
Gene Name		secreted phosphoprotein 1	Sjogren syndrome antigen B (autoantigen La)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleus Ribonucleoprotein Complex
	Molecular Function	Cytokine Activity Protein Binding Extracellular Matrix Binding	TRNA Binding Nucleotide Binding MRNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Osteoblast Differentiation Inflammatory Response Cell Adhesion Embryo Implantation Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Biomineral Tissue Development Response To Vitamin D Positive Regulation Of Bone Resorption Decidualization Response To Steroid Hormone Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury	TRNA Modification Histone MRNA Metabolic Process
Pathways		Signaling by PDGF Integrin cell surface interactions Degradation of the extracellular matrix	RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Protein-Protein Interactions		88 interactors: ABCF3 ACP5 AFF4 AMOTL2 APOA1 ATP2A2 ATP5F1 BAG6 BRD3 C1RL C2orf50 CACNG4 CALM1 CC2D1B CD44 CEP162 CHD1 CISD2 CMTM3 COMMD1 COPS5 CSNK2A1 CSNK2A2 CTNNBL1 CYB5R3 DCX DNAJB1 DNTTIP2 DSEL EEF1A1 EIF3K EPAS1 F2 FTH1 GRIPAP1 HBA2 HMGN1 IGFBP5 ITGA5 ITGA9 ITGAV ITGB1 KCNIP1 LRRC4 MAP1A MAP1B MARCKS MEOX2 MMP3 MMP7 MPPED1 MRPL23 NACA NCKAP1 NCSTN PDLIM7 PEMT PEPD PLD3 PRKACB PRKCA PRKG1 RANBP9 RAPGEF2 RBBP6 RIMS4 RPL13 RPL15 RPL5 RPS13 SEC24C SGTA SLC39A6 SNAPIN SSB STAU1 STK39 TBC1D8 TMEM168 TMEM30A TPT1 TTC1 TUBB UBQLN4 USP42 USP8 ZNF638 ZNF804A	9 interactors: APP CSNK2A1 CSNK2B GZMH HMGA1 IL7R NCL SPIB SPP1
Entrez ID		6696	6741
HPRD ID		01325	00168
Ensembl ID		ENSG00000118785	ENSG00000138385
Uniprot IDs		B7Z351 P10451 Q3LGB0	P05455
PDB IDs		3CXD 3DSF	1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
Enriched GO Terms of Interacting Partners?		Wound Healing Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Neuron Projection Development Response To Wounding Chemotaxis Locomotion Membrane Organization Cell Projection Organization Axon Development Neuron Development Developmental Process Regulation Of Body Fluid Levels Cellular Localization Extracellular Matrix Organization Regulation Of Proteasomal Protein Catabolic Process Extracellular Structure Organization Chemical Homeostasis Anatomical Structure Development Axon Guidance Axonogenesis System Development Leukocyte Migration Translational Initiation Viral Process Ion Homeostasis Regulation Of Cellular Process Nervous System Development Multicellular Organismal Development Cell Migration Neuron Differentiation Metal Ion Homeostasis Cell Morphogenesis Involved In Neuron Differentiation Translational Elongation Immune System Process Integrin-mediated Signaling Pathway Viral Life Cycle Anatomical Structure Morphogenesis Cell Motility Homeostatic Process Neuron Projection Morphogenesis Heterotypic Cell-cell Adhesion Response To Stress Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Regulation Of Protein Metabolic Process	Chemotaxis Developmental Process Response To External Stimulus Axon Guidance Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cell Morphogenesis Cell Differentiation Positive Regulation Of Metabolic Process Interleukin-7-mediated Signaling Pathway Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Oncogene-induced Cell Senescence Synaptic Growth At Neuromuscular Junction Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Locomotion Axonogenesis Anatomical Structure Morphogenesis Axon Development Regulation Of Cell Size Collateral Sprouting In Absence Of Injury Senescence-associated Heterochromatin Focus Assembly Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Growth Cell Growth Neuron Projection Morphogenesis Positive Regulation Of Cellular Senescence System Development Movement Of Cell Or Subcellular Component Positive Regulation Of Gene Expression Generation Of Neurons Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of T Cell Mediated Cytotoxicity Cell Morphogenesis Involved In Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Neurogenesis Negative Regulation Of Neuron Differentiation Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Negative Regulation Of Chromatin Silencing Negative Regulation Of Axon Regeneration Positive Regulation Of Activin Receptor Signaling Pathway Establishment Of Integrated Proviral Latency Neuron Projection Development Regulation Of Mitotic Cell Cycle Phase Transition Multicellular Organismal Development Cell Projection Morphogenesis Positive Regulation Of Cell Aging Adiponectin-activated Signaling Pathway Regulation Of Cell Cycle Phase Transition Cell Part Morphogenesis
Tagcloud ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose	advocate anticollagen asymptomatic autoantibodies autoantibody blindly cardiolipin certified dealing dsdna ganglioside gm2 harbored israeli la liabilities nc phosphatidylserine polyclonality preponderance pyruvate questioning rheumatological rheumatologist rnp silicone ssa ssdna symptomatic
Tagcloud (Difference) ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose	advocate anticollagen asymptomatic autoantibodies autoantibody blindly cardiolipin certified dealing dsdna ganglioside gm2 harbored israeli la liabilities nc phosphatidylserine polyclonality preponderance pyruvate questioning rheumatological rheumatologist rnp silicone ssa ssdna symptomatic
Tagcloud (Intersection) ?