SMN1 and CSAD

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SMN1	CSAD
Gene Name		survival of motor neuron 1, telomeric	cysteine sulfinic acid decarboxylase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cajal Body Z Disc SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	Sulfinoalanine Decarboxylase Activity Pyridoxal Phosphate Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly Nervous System Development Gene Expression NcRNA Metabolic Process	Sulfur Amino Acid Metabolic Process Sulfur Amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process Taurine Biosynthetic Process Small Molecule Metabolic Process
Pathways		snRNP Assembly Metabolism of non-coding RNA	Degradation of cysteine and homocysteine Sulfur amino acid metabolism Metabolism of amino acids and derivatives
Drugs			Pyridoxal Phosphate L-Cysteine
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		136 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AGAP1 APLP1 ARFGAP1 ATP5B ATP6V1A BAG6 BCL2 C19orf60 CARHSP1 CCDC90B CENPB COIL COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CSAD DDAH2 DDX20 DHX9 DMPK DOCK7 DUS2 DYNC1I1 EEF1A1 EIF3G EXT2 EZH2 FAM20C FBL FGB FLAD1 FUBP1 GAPDH GAR1 GDF9 GEMIN2 GEMIN5 GEMIN7 HADHB HIST3H3 HMGXB3 HNRNPR HNRNPU HNRNPUL1 IGHM ILF3 IMMT INPP5K JADE1 KDM1A KIF5A KLHL5 KMT2B KPNB1 LENG8 LRIF1 LSM1 LSM10 LSM11 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAST2 MED31 MKI67 MPP1 MRPL37 MSH2 NGFR NKIRAS2 NMT2 OSTF1 PDE4DIP PKM PLXNA3 POLR2A POP7 PSME1 QARS RBBP4 RBBP6 RBFOX2 RBM48 RN7SL1 RNU1-1 RNU2-1 RPL13 RPS2 RXRA SDF4 SEMA5B SETDB1 SMC5 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNUPN SP110 STRAP STXBP2 STXBP3 SULT1A3 SUMO3 SYNCRIP TAF1C TIAL1 TLE1 TMSB4X TP53 TRMT2A TUBA1A TUBB3 UCHL1 UNC119 USP4 WDR18 WDR73 WDYHV1 WIZ ZBTB16 ZNF431 ZRANB2 ZXDC	10 interactors: ANXA1 ANXA7 CDKN1A GSK3B NR1H2 PIN1 RAP1B RCC1 SMN1 TK1
Entrez ID		6606	51380
HPRD ID		02646	16763
Ensembl ID		ENSG00000172062	ENSG00000139631
Uniprot IDs		B4DP61 Q16637	Q86V02 Q96JQ3 Q9Y600
PDB IDs		1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI	2JIS
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Metabolic Process Spliceosomal SnRNP Assembly Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Macromolecular Complex Assembly Histone MRNA Metabolic Process Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cellular Process Nuclear-transcribed MRNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Component Assembly MRNA Catabolic Process RNA Catabolic Process CRD-mediated MRNA Stabilization Regulation Of Protein Metabolic Process Termination Of RNA Polymerase II Transcription Regulation Of Cellular Protein Metabolic Process DNA-templated Transcription, Termination RNA Biosynthetic Process MRNA 3'-end Processing Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Transcription, DNA-templated RNA 3'-end Processing Regulation Of Mitotic Cell Cycle Phase Transition Spliceosomal Complex Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Phase Transition Developmental Process Regulation Of Metabolic Process Cellular Macromolecule Catabolic Process Cell Differentiation Catabolic Process	Regulation Of Cellular Component Organization Response To Organic Cyclic Compound Response To Organic Substance Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Transport Positive Regulation Of Fatty Acid Biosynthetic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Ras GTPase Activity Response To Inorganic Substance Response To Steroid Hormone Regulation Of Cellular Localization Positive Regulation Of Hydrolase Activity Response To Glucocorticoid Regulation Of Cell Cycle Process Cellular Response To Organic Substance Response To Corticosteroid Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Ras GTPase Activity Epithelial Cell Differentiation Response To X-ray Positive Regulation Of Protein Metabolic Process Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Protein Transport Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Ras Protein Signal Transduction Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Phosphorylation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Regulation Of Protein Localization Positive Regulation Of Cellular Metabolic Process Response To Lipid Positive Regulation Of Lipid Biosynthetic Process Positive Regulation Of Phosphorylation Response To Metal Ion Cellular Response To Heat Positive Regulation Of Protein Modification Process Tissue Development Regulation Of Organelle Organization Regulation Of Vesicle-mediated Transport Regulation Of Cell Cycle Response To Hormone Positive Regulation Of High-density Lipoprotein Particle Assembly Neutrophil Clearance Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion
Tagcloud ?		atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn2 splice unusually weakness	ado birth blotting born cdo deficiency died disruption drinking engineered g2 g3 gpx hplc indicated ko lactoferrin northern offspring physiological prolactin restored southern studying supplementation survived taurine taut verified
Tagcloud (Difference) ?		atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn2 splice unusually weakness	ado birth blotting born cdo deficiency died disruption drinking engineered g2 g3 gpx hplc indicated ko lactoferrin northern offspring physiological prolactin restored southern studying supplementation survived taurine taut verified
Tagcloud (Intersection) ?