WNK1 and CSDE1

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		WNK1	CSDE1
Gene Name		WNK lysine deficient protein kinase 1	cold shock domain containing E1, RNA-binding
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Mitochondrial Inner Membrane Golgi Apparatus Plasma Membrane CRD-mediated MRNA Stability Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Chloride Channel Inhibitor Activity Phosphatase Binding	DNA Binding Poly(A) RNA Binding
	Biological Process	Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Ion Transport Negative Regulation Of Phosphatase Activity Peptidyl-threonine Phosphorylation Intracellular Signal Transduction Neuron Development Regulation Of Cellular Process	Regulation Of Transcription, DNA-templated Male Gonad Development Nuclear-transcribed MRNA Catabolic Process, No-go Decay
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: ADRB2 AKT1 ARAF ATP8 ATXN1 BAG3 CLTC COPS5 CSDE1 E2F3 FHL3 FLNC GLIS2 KLHL2 MAP2K1 MAP3K2 MAP3K3 NEDD4L PFKP PRKAR1A PRKAR1B PVR RANBP9 RBX1 SLC9A1 SUMO1 SYT2 TNRC6A TSC22D1 UBC UPF2 WNK2 YWHAE YWHAG YWHAZ ZNF106 ZYX	8 interactors: FAM9B HID1 HNRNPD PABPC1 PCSK7 STT3A SYNCRIP WNK1
Entrez ID		65125	7812
HPRD ID		05570	15949
Ensembl ID		ENSG00000060237	ENSG00000009307
Uniprot IDs		A5D8Z4 F5GWT4 H6WZW3 Q9H4A3	G5E9Q2 O75534
PDB IDs			1WFQ 1X65 2YTV 2YTX 2YTY
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Sodium Ion Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Intracellular Transport Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Sodium Ion Transport Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Growth Factor Cellular Response To Peptide Hormone Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Protein Kinase Activity Response To Fibroblast Growth Factor Cellular Response To Peptide Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Kinase Activity Establishment Of Localization In Cell Signal Transduction Cell Communication Cellular Localization Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Intracellular Signal Transduction Positive Regulation Of Mitochondrion Organization Cellular Response To Organic Substance Regulation Of Cellular Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Regulation Of MAPK Cascade Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Phosphorylation Cellular Response To Mechanical Stimulus Positive Regulation Of Cellular Protein Metabolic Process	Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Stabilization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Translation RNA Splicing MRNA Processing Positive Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Response To Brefeldin A MRNA Metabolic Process RNA Processing Co-translational Protein Modification Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA Catabolic Process Regulation Of Cellular Protein Metabolic Process CRD-mediated MRNA Stabilization Negative Regulation Of Pancreatic Juice Secretion Circadian Regulation Of Translation Regulation Of Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Positive Regulation Of MRNA Catabolic Process Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Polyadenylation Peptide Hormone Processing RNA Polyadenylation
Tagcloud ?		alanine associate cation ccc cccs chloride compromise cotransporters disruption hence knock lens lenses maintain opacification osr1 proline rat regionally spak ste20 subcellular subcellularly susceptibility transcript transcriptase transparency wet	aiming aip alignment boar brms1 chordc1 clues cops6 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?		alanine associate cation ccc cccs chloride compromise cotransporters disruption hence knock lens lenses maintain opacification osr1 proline rat regionally spak ste20 subcellular subcellularly susceptibility transcript transcriptase transparency wet	aiming aip alignment boar brms1 chordc1 clues cops6 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?