THAP1 and MRPL11

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP1	MRPL11
Gene Name		THAP domain containing, apoptosis associated protein 1	mitochondrial ribosomal protein L11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus PML Body	Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408	15 interactors: APP CAMK2B CAMK2D CRYAB FSD2 HMBOX1 HOMEZ JAKMIP2 KRT40 PNMA1 SLC16A9 TAX1BP1 TFCP2 THAP1 VPS52
Entrez ID		55145	65003
HPRD ID		15496	14739
Ensembl ID		ENSG00000131931	ENSG00000174547
Uniprot IDs		Q9NVV9	Q9Y3B7
PDB IDs		2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process	Regulation Of Cellular Response To Heat Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Immune Response Defense Response Cellular Response To Heat Innate Immune Response Inhibitory G-protein Coupled Receptor Phosphorylation Neuromuscular Process Controlling Balance Developmental Cell Growth Regulation Of Cell Cycle Regulation Of Synapse Structure Or Activity Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Activation Of Meiosis Involved In Egg Activation Embryonic Ectodermal Digestive Tract Development Response To Heat Response To Inorganic Substance Collateral Sprouting In Absence Of Injury Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Response To Abiotic Stimulus Peptidyl-serine Phosphorylation Regulation Of Cell Cycle Process Interferon-gamma-mediated Signaling Pathway Neuromuscular Process Regulation Of Generation Of L-type Calcium Current Activation Of Meiosis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Rac Protein Signal Transduction Regulation Of Histone Deacetylase Activity Cellular Response To Interferon-gamma Cell Growth Regulation Of RNA Metabolic Process Immune System Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Ectodermal Cell Differentiation Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Growth Response To Interferon-gamma Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Regulation Of Synaptic Transmission, Cholinergic
Tagcloud ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Difference) ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Intersection) ?