THAP1 and CHD2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP1	CHD2
Gene Name		THAP domain containing, apoptosis associated protein 1	chromodomain helicase DNA binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus PML Body	Nucleus Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Core Promoter Sequence-specific DNA Binding DNA Binding ATP-dependent DNA Helicase Activity ATP Binding Histone Binding Poly(A) RNA Binding
	Biological Process	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Muscle Organ Development Chromatin Modification DNA Duplex Unwinding Hematopoietic Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408	6 interactors: BEND7 MID2 SRPK2 TEKT1 THAP1 TRIM41
Entrez ID		55145	1106
HPRD ID		15496	03669
Ensembl ID		ENSG00000131931	ENSG00000173575
Uniprot IDs		Q9NVV9	O14647
PDB IDs		2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process	Negative Regulation Of Viral Process Nuclear Speck Organization Regulation Of Viral Process Protein Localization To Microtubule Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Entry Into Host Cell Endothelial Cell Proliferation Protein Ubiquitination Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Genome Replication Protein Localization To Cytoskeleton Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Innate Immune Response
Tagcloud ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper	atp block chd1 chromatin chromodomain completion encode exploit helicase hiv host insertional knockdown lifecycle limited mlv must mutagenesis regulators remodeler replication retroviral retroviruses rnai rodent screen specifically variety wide
Tagcloud (Difference) ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper	atp block chd1 chromatin chromodomain completion encode exploit helicase hiv host insertional knockdown lifecycle limited mlv must mutagenesis regulators remodeler replication retroviral retroviruses rnai rodent screen specifically variety wide
Tagcloud (Intersection) ?