THAP1 and ACOT7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP1	ACOT7
Gene Name		THAP domain containing, apoptosis associated protein 1	acyl-CoA thioesterase 7
Image
Gene Ontology Annotations	Cellular Component	Nucleus PML Body	Nucleoplasm Cytoplasm Mitochondrion Cytosol Neuron Projection Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Fatty Acid Catabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process
Pathways
Drugs
Diseases
GWAS			QT interval ( 19305408)
Protein-Protein Interactions		58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408	10 interactors: ATXN1 ATXN1L CAMK2B CRYAB MAGEA6 POT1 TERF1 THAP1 TINF2 UBQLN1
Entrez ID		55145	11332
HPRD ID		15496	12517
Ensembl ID		ENSG00000131931	ENSG00000097021
Uniprot IDs		Q9NVV9	F5GWE2 O00154
PDB IDs		2JTG 2KO0 2L1G	2QQ2
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomerase Activity Regulation Of DNA Replication RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Regulation Of DNA Biosynthetic Process Lung Alveolus Development Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Inhibitory G-protein Coupled Receptor Phosphorylation Regulation Of Cellular Component Organization Response To Abiotic Stimulus Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Activation Of Meiosis Involved In Egg Activation Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Hematopoietic Stem Cell Proliferation Telomere Formation Via Telomerase Positive Regulation Of Cell Division Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Activation Of Meiosis Positive Regulation Of DNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Metabolic Process Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Regulation Of Cell Death Positive Regulation Of Telomerase Activity Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Telomere Maintenance Via Telomerase
Tagcloud ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper	16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Difference) ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper	16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Intersection) ?