P4HB and CD1D

Number of citations of the paper that reports this interaction (PMID 11257307)
1

Data Source:
HPRD (in vitro)

		P4HB	CD1D
Gene Name		prolyl 4-hydroxylase, beta polypeptide	CD1d molecule
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Focal Adhesion Procollagen-proline 4-dioxygenase Complex Melanosome Extracellular Vesicular Exosome	Cytoplasm Lysosomal Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Endopeptidase Activity Procollagen-proline 4-dioxygenase Activity Protein Binding Enzyme Binding Poly(A) RNA Binding Protein Heterodimerization Activity	Receptor Activity Beta-2-microglobulin Binding Lipid Antigen Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Histone Binding Cell Adhesion Molecule Binding Lipopeptide Binding
	Biological Process	Response To Reactive Oxygen Species Protein Folding Proteolysis Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Extracellular Matrix Organization Response To Endoplasmic Reticulum Stress Lipoprotein Metabolic Process Small Molecule Metabolic Process Cell Redox Homeostasis Cellular Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Viral Process Detection Of Bacterium Heterotypic Cell-cell Adhesion Positive Regulation Of T Cell Proliferation T Cell Selection Innate Immune Response Positive Regulation Of Innate Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Lipoprotein metabolism Hedgehog ligand biogenesis Metabolism of lipids and lipoproteins Collagen formation Chylomicron-mediated lipid transport Processing-defective Hh variants abrogate ligand secretion Detoxification of Reactive Oxygen Species Lipid digestion, mobilization, and transport Signaling by Hedgehog Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: CD1D COL10A1 COL1A1 COL1A2 CSNK2A2 EIF2S1 ERO1L ERO1LB FEZ1 HNRNPD P4HA2 P4HA3 PRNP PTN TG UBQLN1 YWHAG	7 interactors: B2M CALR CANX CD74 P4HB PTPRC TRB
Entrez ID		5034	912
HPRD ID		07181	01780
Ensembl ID		ENSG00000185624	ENSG00000158473
Uniprot IDs		B3KTQ9 B4DUA5 F5H8J2 P07237	P15813
PDB IDs		1BJX 1MEK 1X5C 2BJX 2K18 3BJ5 3UEM 4EKZ 4EL1	1ZT4 2PO6 3HUJ 3SDX 3TZV 3U0P 3VWJ 3VWK 4EN3 4LHU
Enriched GO Terms of Interacting Partners?		4-hydroxyproline Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Collagen Catabolic Process Protein Maturation By Protein Folding Cellular Modified Amino Acid Metabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Protein Heterotrimerization Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Peptidyl-proline Hydroxylation Protein Hydroxylation System Development Response To Endoplasmic Reticulum Stress Developmental Process Protein Trimerization Protein Maturation Endochondral Ossification Multicellular Organismal Development Anatomical Structure Development Skin Morphogenesis Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Cellular Response To Fluoride Cellular Response To Amino Acid Stimulus Collagen Fibril Organization Alpha-amino Acid Metabolic Process Ossification Cellular Response To Organic Substance Biomineral Tissue Development Locomotion Response To Fluoride Tooth Eruption Cellular Response To Stimulus Endochondral Bone Morphogenesis Regulation Of Cellular Protein Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Response To Stimulus Axon Guidance ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Protein Metabolic Process Movement Of Cell Or Subcellular Component Response To Amino Acid Response To Oxidative Stress Protein Oligomerization Cell Redox Homeostasis Bone Morphogenesis	Protein Folding Antigen Processing And Presentation Of Peptide Antigen Chaperone-mediated Protein Folding Antigen Processing And Presentation T Cell Differentiation In Thymus Positive Thymic T Cell Selection Negative Thymic T Cell Selection Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I T Cell Differentiation Negative T Cell Selection Thymic T Cell Selection Positive T Cell Selection Lymphocyte Differentiation Positive Regulation Of Immune System Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Immune System Process Positive Regulation Of B Cell Proliferation Cellular Protein Metabolic Process Leukocyte Cell-cell Adhesion T Cell Selection Homotypic Cell-cell Adhesion Leukocyte Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Positive Regulation Of Cell Adhesion Regulation Of B Cell Proliferation Lymphocyte Activation Positive Regulation Of Leukocyte Chemotaxis Regulation Of Immune System Process Positive Regulation Of B Cell Activation Positive Regulation Of Protein Kinase Activity Metal Ion Homeostasis Homeostatic Process Leukocyte Activation Positive Regulation Of Kinase Activity Protein Metabolic Process Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of T Cell Differentiation Regulation Of Apoptotic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Leukocyte Migration Single Organismal Cell-cell Adhesion Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Lymphocyte Differentiation
Tagcloud ?		anchor anchorage artificial assign bac backcross bacs bands bovine bta19 centromere chrnb1 chromosomes colour construct cryb1 fish gh1 hybrid interspecies library linkage locations loci map meiotic nf1 tp53 unresolved	arranged cd1a cd1b cd1c cd1e cloning code consist cosmid cosmids distant evenly exception histocompatibility linkage mhc microglobulin orientation overlapping pulse relatives serologically spaced spanned thymocyte tight walking wts
Tagcloud (Difference) ?		anchor anchorage artificial assign bac backcross bacs bands bovine bta19 centromere chrnb1 chromosomes colour construct cryb1 fish gh1 hybrid interspecies library locations loci map meiotic nf1 tp53 unresolved	arranged cd1a cd1b cd1c cd1e cloning code consist cosmid cosmids distant evenly exception histocompatibility mhc microglobulin orientation overlapping pulse relatives serologically spaced spanned thymocyte tight walking wts
Tagcloud (Intersection) ?		linkage