HNRNPK and KHDRBS1

Number of citations of the paper that reports this interaction (PMID 12370808)
9

Data Source:
HPRD (in vivo, in vitro)

		HNRNPK	KHDRBS1
Gene Name		heterogeneous nuclear ribonucleoprotein K	KH domain containing, RNA binding, signal transduction associated 1
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Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Membrane Cell Projection Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Membrane Grb2-Sos Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Processing Signal Transduction RNA Splicing Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Viral Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated MRNA Processing Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell Proliferation Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		107 interactors: ABI2 APBB1 AQP5 BTRC C6orf226 CBLB CCAR1 CCDC33 CDKN1A CEBPB CIRBP CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 EIF3F ELAVL1 FBXL18 FYN GFI1B GRAP2 GRB2 GZMA GZMK HCK HIST3H3 HMGB1 HNRNPA0 HNRNPD HNRNPL HNRNPLL ITK ITSN2 KHDRBS1 KHDRBS2 KHDRBS3 LYN MAPK10 MARK4 MATR3 NCK2 NEDD4 NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PELI2 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 PTBP1 QKI RALY RASD1 RBFOX2 RBM10 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RNA18S5 RNA28S5 RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRRT SRSF3 SUMO1 SYNCRIP TBP TCERG1 TERF2IP TYK2 U2AF1 U2AF2 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF792 ZNRF2P1	109 interactors: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK BZRAP1 CBL CD2AP CDK1 CIRBP CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MIA2 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SSFA2 STAT3 STUB1 TBL1X TJP1 TNFSF11 TUBB3 U2AF2 UBA52 UBASH3B VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6
Entrez ID		3190	10657
HPRD ID		02834	03926
Ensembl ID		ENSG00000165119	ENSG00000121774
Uniprot IDs		B4DFF1 B4DUQ1 P61978 Q6IBN1	Q07666
PDB IDs		1J5K 1KHM 1ZZI 1ZZJ 1ZZK	2XA6 3QHE
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Immune Response Positive Regulation Of Metabolic Process MRNA Stabilization Innate Immune Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Metabolic Process Regulation Of Translation Negative Regulation Of Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Immune System Process Positive Regulation Of Gene Expression Regulation Of Immune System Process Defense Response Fc Receptor Signaling Pathway Positive Regulation Of Signal Transduction T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Communication Peptidyl-tyrosine Autophosphorylation Innate Immune Response Signal Transduction Immune Response-regulating Signaling Pathway Immune Response Endocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Locomotion Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of Immune System Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Phagocytosis Cellular Response To Peptide Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Epidermal Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cell Differentiation Regulation Of Catalytic Activity Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Immune System Process Response To Stimulus Regulation Of Signaling Cell Projection Organization Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Metabolic Process
Tagcloud ?		associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Difference) ?		associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Intersection) ?