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GTF2I and C4BPA
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
GTF2I
C4BPA
Gene Name
general transcription factor IIi
complement component 4 binding protein, alpha
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Cell Projection
Neuronal Cell Body
Extracellular Region
Extracellular Space
Plasma Membrane
Other Organism Cell
Blood Microparticle
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Mitogen-activated Protein Kinase Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Transition Between Slow And Fast Fiber
Negative Regulation Of Angiogenesis
Negative Regulation Of Cytosolic Calcium Ion Concentration
Complement Activation, Classical Pathway
Regulation Of Complement Activation
Innate Immune Response
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Complement Activation, Classical Pathway
Regulation Of Opsonization
Pathways
Regulation of Complement cascade
Complement cascade
Innate Immune System
Drugs
Diseases
GWAS
C4b binding protein levels (
20212171
)
Protein-Protein Interactions
35 interactors:
AP2B1
AP4S1
ATF6
BCL2L11
BTK
C4BPA
CALM1
DPY30
GCC1
HDAC3
JAK2
LSM8
MAP3K3
MAPK12
MAPK3
MTUS2
MYC
NFKB2
PIAS2
POU2AF1
PRKG1
PRRX1
SLU7
SMAD2
SNRPN
SRC
SRF
STAT1
STAT3
TAB2
TRAF6
USF1
YY1
ZBTB17
ZMYM3
9 interactors:
APCS
BMPR2
FXYD6
GIT2
GTF2I
LBP
LRP1
PROS1
SMARCD1
Entrez ID
2969
722
HPRD ID
03399
00403
Ensembl ID
ENSG00000077809
ENSG00000123838
Uniprot IDs
A8K9W7
P78347
Q499G6
Q86U51
P04003
Q5VVQ8
PDB IDs
2D9B
2DN4
2ED2
2EJE
2A55
4B0F
Enriched GO Terms of Interacting Partners
?
Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Stress
Positive Regulation Of Gene Expression
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Organic Substance
Positive Regulation Of Cellular Biosynthetic Process
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Stress
RNA Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Gene Expression
Regulation Of RNA Biosynthetic Process
RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Response To Stimulus
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Regulation Of Gene Expression
Cellular Response To Stimulus
Positive Regulation Of Protein Phosphorylation
Growth Hormone Receptor Signaling Pathway
Regulation Of Innate Immune Response
Cellular Response To Growth Hormone Stimulus
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Transferase Activity
Cell Communication
Multicellular Organismal Development
Toll-like Receptor 4 Signaling Pathway
Regulation Of Immune System Process
Regulation Of Locomotion
Acute-phase Response
Regulation Of Inflammatory Response
Artery Development
Negative Regulation Of Wound Healing
Regulation Of Acute Inflammatory Response
Acute Inflammatory Response
Beta-amyloid Clearance
Regulation Of Metabolic Process
Positive Regulation Of Chemotaxis
Positive Regulation Of Respiratory Burst Involved In Inflammatory Response
Leukocyte Chemotaxis Involved In Inflammatory Response
Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity
Negative Regulation By Host Of Viral Glycoprotein Metabolic Process
Regulation Of Lung Blood Pressure
Lipopolysaccharide Transport
Transition Between Slow And Fast Fiber
Negative Regulation Of Exo-alpha-sialidase Activity
Negative Regulation Of Chondrocyte Proliferation
Positive Regulation Of Behavior
Regulation Of Wound Healing
Negative Regulation Of Vasoconstriction
Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Regulation Of Cell Migration
Regulation Of Chemotaxis
Regulation Of Cell Motility
Regulation Of Cellular Component Movement
Regulation Of Behavior
Negative Regulation Of Monocyte Differentiation
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Innate Immune Response
Positive Regulation Of Respiratory Burst
Leukocyte Migration
Positive Regulation Of Axon Extension Involved In Axon Guidance
Regulation Of Skeletal Muscle Adaptation
Lymphatic Endothelial Cell Differentiation
Negative Regulation Of Cytosolic Calcium Ion Concentration
Negative Regulation Of Growth
Negative Regulation Of Locomotion
Phagocytosis
Chromatin-mediated Maintenance Of Transcription
Opsonization
Regulation Of Respiratory Burst
Macrophage Activation Involved In Immune Response
Regulation Of Phospholipase A2 Activity
Positive Regulation Of Macrophage Activation
Lymphangiogenesis
Response To Stress
Positive Regulation Of Toll-like Receptor Signaling Pathway
Negative Regulation Of Glycoprotein Metabolic Process
Tagcloud
?
74146970t
ab
aggressive
assessment
bap1
carcinomas
cdkn2a
classification
complement
cyld
delta
facilitate
indolent
isoforms
missense
mutation
next
notably
pbrm1
rarely
recurrent
sequencing
stimulate
subtype
subtypes
tets
thymic
thymomas
tp53
Tagcloud (Difference)
?
74146970t
ab
aggressive
assessment
bap1
carcinomas
cdkn2a
classification
complement
cyld
delta
facilitate
indolent
isoforms
missense
mutation
next
notably
pbrm1
rarely
recurrent
sequencing
stimulate
subtype
subtypes
tets
thymic
thymomas
tp53
Tagcloud (Intersection)
?