GTF2I and SLU7

Number of citations of the paper that reports this interaction (PMID 18662664)
5

Data Source:
BioGRID (pull down)

		GTF2I	SLU7
Gene Name		general transcription factor IIi	SLU7 splicing factor homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Cell Projection Neuronal Cell Body	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Mitogen-activated Protein Kinase Binding	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Transition Between Slow And Fast Fiber Negative Regulation Of Angiogenesis Negative Regulation Of Cytosolic Calcium Ion Concentration	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Intracellular Protein Transport Cellular Response To Heat
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AP2B1 AP4S1 ATF6 BCL2L11 BTK C4BPA CALM1 DPY30 GCC1 HDAC3 JAK2 LSM8 MAP3K3 MAPK12 MAPK3 MTUS2 MYC NFKB2 PIAS2 POU2AF1 PRKG1 PRRX1 SLU7 SMAD2 SNRPN SRC SRF STAT1 STAT3 TAB2 TRAF6 USF1 YY1 ZBTB17 ZMYM3	17 interactors: BAG2 CCDC85B CEP70 GOLGA2 GTF2I JMJD6 KDM1A KRT40 LZTS2 PCBP2 PPIG PPIL3 PRMT5 PRMT6 THAP1 WHSC1L1 ZCCHC10
Entrez ID		2969	10569
HPRD ID		03399	12074
Ensembl ID		ENSG00000077809	ENSG00000164609
Uniprot IDs		A8K9W7 P78347 Q499G6 Q86U51	O95391
PDB IDs		2D9B 2DN4 2ED2 2EJE
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Gene Expression Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stress RNA Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Response To Stimulus Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Gene Expression Cellular Response To Stimulus Positive Regulation Of Protein Phosphorylation Growth Hormone Receptor Signaling Pathway Regulation Of Innate Immune Response Cellular Response To Growth Hormone Stimulus MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transferase Activity Cell Communication Multicellular Organismal Development Toll-like Receptor 4 Signaling Pathway Regulation Of Immune System Process	RNA Metabolic Process Gene Expression RNA Splicing Histone Modification Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-amino Acid Modification RNA Processing Cellular Nitrogen Compound Metabolic Process Histone H4-R3 Methylation Chromatin Modification Transcription, DNA-templated RNA Biosynthetic Process Peptidyl-arginine N-methylation Nitrogen Compound Metabolic Process Chromatin Organization Histone Methylation Histone Arginine Methylation Peptidyl-arginine Methylation MRNA Processing Protein Methylation Histone Demethylation Protein Demethylation MRNA Metabolic Process Chromosome Organization Cellular Protein Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Cellular Macromolecule Biosynthetic Process Histone H3-R2 Demethylation Histone H4-R3 Demethylation Regulation Of Primitive Erythrocyte Differentiation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Protein Folding Macromolecule Biosynthetic Process Demethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Peptidyl-prolyl Isomerization Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Transition Between Slow And Fast Fiber Organelle Organization Negative Regulation Of Binding Cellular Protein Modification Process
Tagcloud ?		74146970t ab aggressive assessment bap1 carcinomas cdkn2a classification complement cyld delta facilitate indolent isoforms missense mutation next notably pbrm1 rarely recurrent sequencing stimulate subtype subtypes tets thymic thymomas tp53
Tagcloud (Difference) ?		74146970t ab aggressive assessment bap1 carcinomas cdkn2a classification complement cyld delta facilitate indolent isoforms missense mutation next notably pbrm1 rarely recurrent sequencing stimulate subtype subtypes tets thymic thymomas tp53
Tagcloud (Intersection) ?