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GDF9 and PCYT2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
GDF9
PCYT2
Gene Name
growth differentiation factor 9
phosphate cytidylyltransferase 2, ethanolamine
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytoplasm
Cellular_component
Endoplasmic Reticulum Membrane
Molecular Function
Cytokine Activity
Transforming Growth Factor Beta Receptor Binding
Growth Factor Activity
Ethanolamine-phosphate Cytidylyltransferase Activity
Biological Process
Oocyte Growth
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Positive Regulation Of Cell Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
BMP Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of MAPK Cascade
Cell Development
SMAD Protein Signal Transduction
Regulation Of Progesterone Secretion
Phospholipid Metabolic Process
Phosphatidylethanolamine Biosynthetic Process
Phospholipid Biosynthetic Process
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Pathways
Metabolism of lipids and lipoproteins
Synthesis of PE
Phospholipid metabolism
Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions
45 interactors:
ACVR2A
ADPGK
ANXA7
APLP1
BMP15
BMPR1A
BMPR1B
BMPR2
BTBD2
CCDC53
CDKN1A
CDKN2C
CRELD1
DLEU1
DNM2
FOXG1
FXYD6
GADD45G
ILF3
KDM1A
KIF22
LSM3
MOB4
MPHOSPH6
MYCBP
NDUFB9
ORAI2
PABPC4
PAFAH1B3
PCDHA4
PCYT2
PMF1
PRKRA
PSMD11
RAB27A
RSRC1
S100A8
SAT1
SERPINB9
SMN1
SNRPG
STRN4
TDGF1
TK1
TRIB3
6 interactors:
ADAMTS10
CRIP2
DNMT3B
GDF9
KDM8
SETDB1
Entrez ID
2661
5833
HPRD ID
03560
04059
Ensembl ID
ENSG00000164404
Uniprot IDs
B4DXG3
O60383
B3KSC8
B7Z4W6
B7ZAS0
Q99447
PDB IDs
3ELB
Enriched GO Terms of Interacting Partners
?
BMP Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Chondrocyte Proliferation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Developmental Process
Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Differentiation
Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Anatomical Structure Development
Positive Regulation Of Protein Modification Process
Nucleobase-containing Compound Metabolic Process
System Development
Cellular Nitrogen Compound Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Ossification
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Signal Transduction
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Immune System Process
Regulation Of Cell Death
RNA Metabolic Process
RNA Processing
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Osteoblast Differentiation
Gene Expression
Negative Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Transferase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Gene Expression
Regulation Of Phosphorylation
Regulation Of Cell Growth
Organ Development
Gastrulation
Positive Regulation Of Metabolic Process
Chromatin Modification
Oocyte Growth
Chromatin Organization
S-adenosylmethioninamine Metabolic Process
DNA Methylation On Cytosine Within A CG Sequence
Regulation Of Progesterone Secretion
C-5 Methylation Of Cytosine
S-adenosylhomocysteine Metabolic Process
Chromosome Organization
Histone H3-K36 Demethylation
Methylation-dependent Chromatin Silencing
Developmental Growth
Histone H3-K9 Trimethylation
Negative Regulation Of Histone H3-K9 Methylation
DNA Methylation On Cytosine
Regulation Of Female Gonad Development
Histone Modification
Positive Regulation Of Histone H3-K4 Methylation
Methylation
Negative Regulation Of Histone Methylation
Protein Complex Localization
Histone H3-K9 Methylation
Inner Cell Mass Cell Proliferation
Tagcloud
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Difference)
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Intersection)
?