GBP2 and BNIP3L

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GBP2	BNIP3L
Gene Name		guanylate binding protein 2, interferon-inducible	BCL2/adenovirus E1B 19kDa interacting protein 3-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Cytosol Symbiont-containing Vacuole Membrane Cytoplasmic Vesicle	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Integral Component Of Membrane Intrinsic Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Immune Response Metabolic Process Cytokine-mediated Signaling Pathway Cellular Response To Interferon-beta Defense Response To Protozoan Adhesion Of Symbiont To Host Defense Response To Gram-positive Bacterium Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Lipopolysaccharide	Viral Process Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Defense Response To Virus Mitochondrial Outer Membrane Permeabilization
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ANXA7 BID BNIP3L BTBD2 CSNK2B FXR1 GADD45A GSK3B HSPE1 KLHL20 LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG	23 interactors: BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 DOK5 DUSP3 ECM1 EWSR1 FATE1 GBP2 GNB5 KLHL23 LDLRAD1 MAP1LC3A RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11
Entrez ID		2634	665
HPRD ID		02682	07288
Ensembl ID		ENSG00000162645	ENSG00000104765
Uniprot IDs		P32456 Q8TCE5	B0AZS9 B4DTN1 O60238 Q6IBV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Death Death Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Positive Regulation Of Cell Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Mitochondrial Outer Membrane Permeabilization Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of MAPK Cascade Hepatocyte Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Regulation Of Protein Phosphorylation Apoptotic Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Response To Stimulus Positive Regulation Of Protein Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Regulation Of Protein Kinase Activity Regulation Of Peptidase Activity Regulation Of JNK Cascade Regulation Of Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Kinase Activity Regulation Of Mitochondrial Membrane Permeability Catabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Membrane Permeability Regulation Of Stress-activated MAPK Cascade Regulation Of Phosphorylation Social Behavior Positive Regulation Of Phosphorylation Response To Organic Substance	Mitochondrial Membrane Organization Mitochondrion Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Defense Response Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Mitochondrial Changes Response To External Stimulus Regulation Of Mitochondrion Organization Ovulation Cycle Process Negative Regulation Of Anoikis Positive Regulation Of Apoptotic Process Regulation Of Autophagy Female Gonad Development Positive Regulation Of Programmed Cell Death Ovulation Cycle Regulation Of Anoikis Development Of Primary Female Sexual Characteristics Positive Regulation Of Cell Death Regulation Of Response To DNA Damage Stimulus Response To Stress Defense Response To Protozoan Regulation Of Signal Transduction Response To Protozoan Response To Other Organism Release Of Cytochrome C From Mitochondria Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Biotic Stimulus Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Negative Regulation Of Mitochondrion Organization Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Signaling Positive Regulation Of Signal Transduction Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway Cellular Response To Organic Substance Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Calcium Ion Transport Membrane Organization Negative Regulation Of Calcium Ion Transport Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Process
Tagcloud ?		anthracycline besides carcinomas chemotherapy erbb2 fast grading guanylate hazard inducible infiltration interestingly interferon kappa metalloproteinase node odds pathologically probably prognosis proliferating pt rac reach receive represents signature subgroups univariate	abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation
Tagcloud (Difference) ?		anthracycline besides carcinomas chemotherapy erbb2 fast grading guanylate hazard inducible infiltration interestingly interferon kappa metalloproteinase node odds pathologically probably prognosis proliferating pt rac reach receive represents signature subgroups univariate	abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation
Tagcloud (Intersection) ?