GBP2

Gene Name		guanylate binding protein 2, interferon-inducible
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Cytosol Symbiont-containing Vacuole Membrane Cytoplasmic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding
	Biological Process	Immune Response Metabolic Process Cytokine-mediated Signaling Pathway Cellular Response To Interferon-beta Defense Response To Protozoan Adhesion Of Symbiont To Host Defense Response To Gram-positive Bacterium Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		21 interactors: ANXA7 BID BNIP3L BTBD2 CSNK2B FXR1 GADD45A GSK3B HSPE1 KLHL20 LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG
Entrez ID		2634
HPRD ID		02682
Ensembl ID		ENSG00000162645
Uniprot IDs		P32456 Q8TCE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Death Death Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Positive Regulation Of Cell Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Mitochondrial Outer Membrane Permeabilization Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of MAPK Cascade Hepatocyte Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Regulation Of Protein Phosphorylation Apoptotic Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Response To Stimulus Positive Regulation Of Protein Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Regulation Of Protein Kinase Activity Regulation Of Peptidase Activity Regulation Of JNK Cascade Regulation Of Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Kinase Activity Regulation Of Mitochondrial Membrane Permeability Catabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Membrane Permeability Regulation Of Stress-activated MAPK Cascade Regulation Of Phosphorylation Social Behavior Positive Regulation Of Phosphorylation Response To Organic Substance
Tagcloud ?		anthracycline besides carcinomas chemotherapy erbb2 fast grading guanylate hazard inducible infiltration interestingly interferon kappa metalloproteinase node odds pathologically probably prognosis proliferating pt rac reach receive represents signature subgroups univariate