Gene Name |
estrogen receptor 2 (ER beta) |
mesenchyme homeobox 2 |
Image |
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No pdb structure |
Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Diethylstilbestrol
- Raloxifene
- Tamoxifen
- Estradiol
- Trilostane
- Estramustine
- Genistein
- Para-Mercury-Benzenesulfonic Acid
- N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide
- 5-Alpha-Androstane-3-Beta,17beta-Diol
- 4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol
- Estriol
- Estropipate
- 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL
- 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL
- 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
- 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL
- (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol
- 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
- 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
- 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
- 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
- 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
- (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- (16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL
- (9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
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Diseases |
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GWAS |
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- Blood trace element (Zn levels) ( 23720494)
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Protein-Protein Interactions |
88 interactors:
AKAP13
AKT1
ARID5A
BCAS2
CALM1
CALM2
CALM3
CCNC
CDK8
DAP3
DDX17
DDX5
DDX54
DNTTIP2
EIF3I
EP300
ESR1
JMJD1C
KAT5
LCK
MAD2L1
MAPK1
MAPK11
MED1
MED10
MED12
MED14
MED16
MED17
MED20
MED21
MED23
MED24
MED6
MED7
MEOX2
MKNK2
MMS19
MSH2
NCOA1
NCOA2
NCOA3
NCOA6
NCOA7
NCOR1
NCOR2
NFKBIB
NOTCH2NL
NR0B1
NR0B2
NRIP1
OXT
PELP1
PIAS1
PIAS2
PIAS3
PLSCR1
PNRC1
PNRC2
PPARG
PPARGC1A
PPP5C
PRMT2
PSMC3IP
RBFOX2
RBM39
REXO4
RFX6
RXRA
SERPINH1
SMAD2
SMAD3
SMAD4
SMARCE1
SP1
SRA1
SRC
SREBF1
STAT5A
TRAM1
TRIM24
TRIM59
TRIP4
WIPI1
YWHAH
YWHAQ
ZBTB17
ZNHIT3
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207 interactors:
ADAMTS12
AGPAT1
AHCYL1
AHSA2
ANP32B
ARHGEF7
ARNT2
ATG5
ATXN1L
BCL2L15
C19orf66
C1orf109
CARD9
CASP14
CCDC103
CCNC
CDH9
CEP57L1
CHIC2
CHRD
CIAPIN1
CIB3
CNTNAP2
COX1
CPNE6
CPSF4
CRCT1
CSDC2
CSF2
CTNNBL1
CXXC1
DGCR6
DGCR8
DOCK8
DYNLL2
EDF1
EFEMP2
EFNA3
EIF1AD
EIF5A
EPM2AIP1
ESR2
ESRRG
FAM13C
FAM3A
FAM74A4
FBF1
FOXR1
FUCA2
FUT11
GABRB3
GAGE1
GLO1
GMCL1P1
GMPR2
GNG11
GOLGA8DP
GOLGA8EP
GOLGA8F
GPATCH2L
GPSM3
HAT1
HDHD2
HEXIM2
HGF
HLA-A
HNRNPD
HP1BP3
HSPA2
HTR1E
IGF2BP3
IGFN1
INPP1
IP6K2
ITM2A
KAT5
KIZ
KLC4
KLHL38
KRT80
KRT86
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-4
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KTN1
LAMTOR5
LCE1B
LCE2A
LCE4A
LOC153684
LSM2
MAGED1
MAPKBP1
MKRN3
MLLT6
MMP3
MORN3
MRFAP1L1
MSI2
MT1DP
MTMR10
MUM1
MVP
MYBPC1
NAA10
NALCN
NCALD
NCK2
ND1
NLGN3
NTF3
OIT3
OSGIN1
P4HA3
PACSIN2
PAGE2
PARK2
PARVG
PAX1
PAX3
PCDH9
PCSK5
PGBD1
PIN1
PKIG
POM121C
PRKAB2
PRR19
PSMB10
PSMC1
PSMD14
PTGER3
RARB
RCHY1
RECK
RHOJ
RMND5A
RND2
RPL15
RUNX1T1
SAMM50
SCNM1
SEPP1
SET
SIRPB1
SLC48A1
SMAD3
SMARCE1
SPATA1
SPP1
SPRY1
SPRY2
SSX3
STK16
STX11
STX16
SYT17
TBCEL
TBX6
TCEA2
TCL6
TCTEX1D1
TDO2
TGFB1
TICAM2
TMEM100
TP53BP1
TRAF6
TRIM41
TRIM42
TTC25
TTC39B
TTC9C
TULP2
TXLNA
UBE3A
UBL4A
UBL4B
UNC45A
USE1
VEZF1
VIP
WFDC9
XRCC2
ZBED4
ZMAT2
ZNF124
ZNF329
ZNF404
ZNF417
ZNF483
ZNF564
ZNF572
ZNF587
ZNF695
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Entrez ID |
2100 |
4223 |
HPRD ID |
03390 |
02760 |
Ensembl ID |
ENSG00000140009
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ENSG00000106511
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Uniprot IDs |
F1D8N3
G3V5M5
Q0PTK2
Q7LCB3
Q92731
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P50222
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PDB IDs |
1L2J
1NDE
1QKM
1U3Q
1U3R
1U3S
1U9E
1X76
1X78
1X7B
1X7J
1YY4
1YYE
1ZAF
2FSZ
2GIU
2I0G
2JJ3
2NV7
2QTU
2YJD
2YLY
2Z4B
3OLL
3OLS
3OMO
3OMP
3OMQ
4J24
4J26
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
25mg
acrosomes
bisphenol
bpa
compromises
disrupts
dosages
epididymis
esr1
fsh
fshb
gnrhr
gonadal
gonadotropin
hypogonadism
hypogonadotropic
hypothalamic
lh
lhb
luteinizing
nontoxic
pituitary
reestablish
reproductive
reserves
sperm
spermatogenesis
spermatozoa
transit
|
activates
angiogenic
biphasic
colocalization
colocalizes
constructs
depend
ec
ecs
homeobox
homeodomain
homeoprotein
hypothesize
ikappabbeta
immunofluorescence
implicate
ingrowth
modulate
modulates
normally
p65
proangiogenic
promoters
rela
represses
secrete
stimulates
transduced
vessels
|
Tagcloud (Difference) ? |
25mg
acrosomes
bisphenol
bpa
compromises
disrupts
dosages
epididymis
esr1
fsh
fshb
gnrhr
gonadal
gonadotropin
hypogonadism
hypogonadotropic
hypothalamic
lh
lhb
luteinizing
nontoxic
pituitary
reestablish
reproductive
reserves
sperm
spermatogenesis
spermatozoa
transit
|
activates
angiogenic
biphasic
colocalization
colocalizes
constructs
depend
ec
ecs
homeobox
homeodomain
homeoprotein
hypothesize
ikappabbeta
immunofluorescence
implicate
ingrowth
modulate
modulates
normally
p65
proangiogenic
promoters
rela
represses
secrete
stimulates
transduced
vessels
|
Tagcloud (Intersection) ? |
|