EEF1G and NUP85

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1G	NUP85
Gene Name		eukaryotic translation elongation factor 1 gamma	nucleoporin 85kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Vesicular Exosome	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Spindle Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane
	Molecular Function	Translation Elongation Factor Activity Protein Binding	Protein Binding
	Biological Process	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Lamellipodium Assembly Small Molecule Metabolic Process Macrophage Chemotaxis MRNA Transport Transmembrane Transport
Pathways		Translation Eukaryotic Translation Elongation	Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	5 interactors: DYNC1LI1 EEF1G PIK3R1 PRKACA VIM
Entrez ID		1937	79902
HPRD ID		11745	01363
Ensembl ID		ENSG00000254772	ENSG00000125450
Uniprot IDs		P26641 Q53YD7	B4DYG7 Q9BW27
PDB IDs		1PBU
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity	Regulation Of Glucose Import Movement Of Cell Or Subcellular Component Cellular Glucose Homeostasis Viral Process Cellular Response To Light Stimulus Regulation Of Glucose Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Dense Core Granule Biogenesis NFAT Protein Import Into Nucleus Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Mitotic Cell Cycle Cellular Response To Radiation Histone H3-T6 Phosphorylation Transcription Factor Import Into Nucleus Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Myeloid Cell Differentiation Intrinsic Apoptotic Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Apoptotic Process Response To Fibroblast Growth Factor Platelet Activation Programmed Cell Death Glucose Homeostasis Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Leukocyte Migration Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Intracellular Transport Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Regulation Of Intracellular Protein Transport Peptidyl-serine Autophosphorylation Positive Regulation Of Spindle Checkpoint Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Positive Regulation Of Cell Cycle Bergmann Glial Cell Differentiation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Positive Regulation Of Cell Migration Desmosome Assembly
Tagcloud ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Difference) ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Intersection) ?