EEF1G and SNRPD2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		EEF1G	SNRPD2
Gene Name		eukaryotic translation elongation factor 1 gamma	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Vesicular Exosome	Nucleoplasm Spliceosomal Complex U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Translation Elongation Factor Activity Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression NcRNA Metabolic Process
Pathways		Translation Eukaryotic Translation Elongation	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing snRNP Assembly mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	25 interactors: CEP70 CLNS1A DDX20 DMTN EEF1G EGFR GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF STRAP STXBP2 STXBP3 WDR77 ZCCHC10
Entrez ID		1937	6633
HPRD ID		11745	03038
Ensembl ID		ENSG00000254772	ENSG00000125743
Uniprot IDs		P26641 Q53YD7	P62316
PDB IDs		1PBU	1B34 1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly RNA Splicing MRNA Processing Ribonucleoprotein Complex Biogenesis MRNA Metabolic Process RNA Processing NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Cellular Component Assembly Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Cellular Response To Estradiol Stimulus Neutrophil Mediated Immunity Neutrophil Activation Cellular Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Response To Estrogen Stimulus Cellular Process Leukocyte Degranulation Alkanesulfonate Metabolic Process Positive Regulation Of Platelet Aggregation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Protein Secretion By Platelet Calcium-mediated Signaling Using Extracellular Calcium Source Interleukin-7-mediated Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Vesicle Docking Regulation Of Epithelial Cell Proliferation Actin Filament Reorganization Membrane Docking Activation Of Phospholipase A2 Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Calcium-mediated Signaling Cell Activation Exocytosis
Tagcloud ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Difference) ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Intersection) ?