GADD45G and SMARCB1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GADD45G	SMARCB1
Gene Name		growth arrest and DNA-damage-inducible, gamma	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin XY Body Nucleus Nucleoplasm Nucleolus SWI/SNF Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding P53 Binding Transcription Coactivator Activity Protein Binding Tat Protein Binding Nucleosomal DNA Binding
	Biological Process	Activation Of MAPKKK Activity Activation Of MAPKK Activity Negative Regulation Of Protein Kinase Activity Apoptotic Process Response To Stress Multicellular Organismal Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade	Blastocyst Hatching DNA Repair Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Negative Regulation Of Cell Proliferation DNA Integration Cell Differentiation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate ATP-dependent Chromatin Remodeling Positive Regulation By Host Of Viral Transcription Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)	IgG glycosylation ( 23382691)
Protein-Protein Interactions		55 interactors: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579	40 interactors: AKT1 APP BCL2L11 CALR CDX2 CEBPB DPF2 DPF3 GADD45G GATA1 KLF1 KMT2B KMT2C MAP1LC3B MAPK8IP2 MCPH1 MECP2 MYC NONO NR0B2 NR3C1 PDPK1 PPP1CC PPP1R15A PRMT5 RAN RB1 RELB RPS6KA5 SIN3B SMARCA4 SRC TACC2 TAF1D TP53 UBQLN4 XPO1 YEATS4 ZAK ZDHHC17
Entrez ID		10912	6598
HPRD ID		05383	03364
Ensembl ID		ENSG00000130222	ENSG00000099956
Uniprot IDs		O95257 Q5VZ87	G5E975 Q12824 Q9H836
PDB IDs		2WAL 3FFM
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Ventricular Cardiac Muscle Cell Differentiation Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Fibroblast Proliferation Response To Organic Cyclic Compound Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To Lipid Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Kinase Activity Regulation Of Growth Response To Steroid Hormone Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction	Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Chromatin Organization Positive Regulation Of Metabolic Process Organelle Organization Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Chromatin Modification Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Chromosome Organization Regulation Of Cellular Process RNA Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Organ Development Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation System Development Regulation Of Signaling Developmental Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Negative Regulation Of Signal Transduction Regulation Of Phosphorylation Anatomical Structure Development Regulation Of Organelle Organization Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Phosphorus Metabolic Process
Tagcloud ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Difference) ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Intersection) ?