GADD45G and SH3GLB2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GADD45G	SH3GLB2
Gene Name		growth arrest and DNA-damage-inducible, gamma	SH3-domain GRB2-like endophilin B2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Activation Of MAPKKK Activity Activation Of MAPKK Activity Negative Regulation Of Protein Kinase Activity Apoptotic Process Response To Stress Multicellular Organismal Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade
Pathways
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		55 interactors: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579	8 interactors: CCDC158 GADD45G GIT2 KDM1A MAGEA1 SH3GLB1 SH3KBP1 SREK1
Entrez ID		10912	56904
HPRD ID		05383	15334
Ensembl ID		ENSG00000130222	ENSG00000148341
Uniprot IDs		O95257 Q5VZ87	B7ZC38 Q9NR46
PDB IDs		2WAL 3FFM
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Ventricular Cardiac Muscle Cell Differentiation Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Fibroblast Proliferation Response To Organic Cyclic Compound Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To Lipid Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Kinase Activity Regulation Of Growth Response To Steroid Hormone Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction	Regulation Of Primitive Erythrocyte Differentiation Regulation Of Signal Transduction Regulation Of Signaling Apoptotic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Programmed Cell Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Cell Death Death Negative Regulation Of Signal Transduction Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of P38MAPK Cascade Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Protein Oligomerization Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Behavioral Response To Pain Regulation Of Histone H3-K4 Methylation
Tagcloud ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo	analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l plxna3 protamines semen semiquantitative sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Difference) ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo	analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l plxna3 protamines semen semiquantitative sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Intersection) ?