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ARHGAP22 - Wiki-MPM

Search Results for: ARHGAP22

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ALG11 ALG11 alpha-1,2-mannosyltransferase
  • Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
  • Defective ALG11 causes ALG11-CDG (CDG-1p)
Novel GPRIN2 G protein regulated inducer of neurite outgrowth 2
Novel MAPK8 mitogen-activated protein kinase 8
  • Activation of BIM and translocation to mitochondria
  • Activation of BMF and translocation to mitochondria
  • NRAGE signals death through JNK
  • NRAGE signals death through JNK
  • NRIF signals cell death from the nucleus
  • Oxidative Stress Induced Senescence
  • FCERI mediated MAPK activation
  • DSCAM interactions
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • Activation of the AP-1 family of transcription factors
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Interleukin-38 signaling
  • WNT5:FZD7-mediated leishmania damping
  • Tamoxifen
  • Minocycline
  • Pyrazolanthrone
  • 6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE
  • 2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE
  • N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE
  • 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE
  • 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide
  • Halicin
Novel PTPN20 protein tyrosine phosphatase non-receptor type 20
  • Interleukin-37 signaling
Novel ZNF488 zinc finger protein 488
CACNA1A calcium voltage-gated channel subunit alpha1 A
  • Presynaptic depolarization and calcium channel opening
  • Regulation of insulin secretion
  • Ergocalciferol
  • Enflurane
  • Phenytoin
  • Spironolactone
  • Magnesium sulfate
  • Verapamil
  • Levomenthol
  • Loperamide
  • Bepridil
  • Ziconotide
  • Dotarizine
  • Trimebutine
  • Benidipine
  • Cilnidipine
  • Lacidipine
  • Manidipine
  • Butamben
  • Bioallethrin
  • Bioallethrin
  • Bioallethrin
  • Episodic ataxias
  • Familial or sporadic hemiplegic migraine
  • Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
CCNDBP1 cyclin D1 binding protein 1
CDC42 cell division cycle 42
  • GPVI-mediated activation cascade
  • EGFR downregulation
  • Rho GTPase cycle
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • CD28 dependent Vav1 pathway
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • DCC mediated attractive signaling
  • Inactivation of CDC42 and RAC1
  • VEGFA-VEGFR2 Pathway
  • Myogenesis
  • Myogenesis
  • RHO GTPases activate KTN1
  • RHO GTPases activate IQGAPs
  • RHO GTPases activate PAKs
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate Formins
  • RHO GTPases Activate Formins
  • MAPK6/MAPK4 signaling
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • G beta:gamma signalling through CDC42
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
  • Factors involved in megakaryocyte development and platelet production
  • Aminophosphonic acid-guanylate ester
  • Guanosine-5'-Diphosphate
DEF6 DEF6 guanine nucleotide exchange factor
IL1RAPL1 interleukin 1 receptor accessory protein like 1
  • Receptor-type tyrosine-protein phosphatases
  • Interleukin-38 signaling
  • Non-syndromic X-linked mental retardation
RAC1 Rac family small GTPase 1
  • GPVI-mediated activation cascade
  • PIP3 activates AKT signaling
  • Signaling by SCF-KIT
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Nef and signal transduction
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • DAP12 signaling
  • FCERI mediated MAPK activation
  • DSCAM interactions
  • CD28 dependent Vav1 pathway
  • EPHB-mediated forward signaling
  • Ephrin signaling
  • EPH-ephrin mediated repulsion of cells
  • Sema3A PAK dependent Axon repulsion
  • SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
  • PCP/CE pathway
  • Sema4D mediated inhibition of cell attachment and migration
  • DCC mediated attractive signaling
  • DCC mediated attractive signaling
  • Activation of RAC1
  • Inactivation of CDC42 and RAC1
  • VEGFA-VEGFR2 Pathway
  • Signal transduction by L1
  • VEGFR2 mediated vascular permeability
  • RHO GTPases activate PKNs
  • RHO GTPases activate CIT
  • RHO GTPases activate CIT
  • RHO GTPases activate KTN1
  • RHO GTPases activate IQGAPs
  • RHO GTPases activate PAKs
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate Formins
  • RHO GTPases Activate Formins
  • RHO GTPases Activate NADPH Oxidases
  • MAPK6/MAPK4 signaling
  • Neutrophil degranulation
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • MET activates RAP1 and RAC1
  • NTRK2 activates RAC1
  • Activated NTRK2 signals through CDK5
  • Activation of RAC1 downstream of NMDARs
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
  • WNT5:FZD7-mediated leishmania damping
  • Factors involved in megakaryocyte development and platelet production
  • Dextromethorphan
  • Azathioprine
  • Guanosine-5'-Diphosphate
RHOA ras homolog family member A
  • GPVI-mediated activation cascade
  • Axonal growth inhibition (RHOA activation)
  • Rho GTPase cycle
  • PI3K/AKT activation
  • Axonal growth stimulation
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • G beta:gamma signalling through PI3Kgamma
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • EPHA-mediated growth cone collapse
  • EPHA-mediated growth cone collapse
  • PCP/CE pathway
  • G alpha (12/13) signalling events
  • Sema4D mediated inhibition of cell attachment and migration
  • Sema4D induced cell migration and growth-cone collapse
  • Sema4D induced cell migration and growth-cone collapse
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases activate PKNs
  • RHO GTPases activate CIT
  • RHO GTPases activate CIT
  • RHO GTPases activate KTN1
  • RHO GTPases Activate ROCKs
  • RHO GTPases Activate ROCKs
  • RHO GTPases Activate Formins
  • RHO GTPases Activate Rhotekin and Rhophilins
  • RHO GTPases Activate Rhotekin and Rhophilins
  • Ovarian tumor domain proteases
  • ERBB2 Regulates Cell Motility
  • Neutrophil degranulation
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • SLIT2:ROBO1 increases RHOA activity
  • Guanosine-5'-Diphosphate

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