ARHGAP22 and IL1RAPL1

Data Source:
BioGRID (pull down)

		ARHGAP22	IL1RAPL1
Description		Rho GTPase activating protein 22	interleukin 1 receptor accessory protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion Glutamatergic Synapse	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Axon Dendrite Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity Protein Binding	Signaling Receptor Binding Protein Binding Interleukin-1 Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating
	Biological Process	Angiogenesis Signal Transduction Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity Regulation Of Postsynapse Organization	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Exocytosis Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Cellular Response To Cytokine Stimulus Presynaptic Membrane Assembly Regulation Of Postsynapse Organization Trans-synaptic Signaling By Trans-synaptic Complex Regulation Of Presynapse Assembly
Pathways		Rho GTPase cycle	Receptor-type tyrosine-protein phosphatases Interleukin-38 signaling
Drugs
Diseases			Non-syndromic X-linked mental retardation
GWAS		Conduct disorder ( 20585324) Daytime sleep phenotypes ( 27126917) Diabetic retinopathy ( 21310492) Macular thickness ( 30535121) Refractive error ( 32231278) Self-employment ( 23593239)	Cardiovascular risk factors (age interaction) ( 20838585) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Vitiligo ( 27723757)
Interacting Genes		7 interacting genes: CACNA1A CCNDBP1 CDC42 DEF6 IL1RAPL1 RAC1 RHOA	2 interacting genes: ARHGAP22 NCS1
Entrez ID		58504	11141
HPRD ID		12476	02193
Ensembl ID		ENSG00000128805	ENSG00000169306
Uniprot IDs		A0A2X0SFC0 Q7Z5H3	Q9NZN1 X5DNQ7
PDB IDs			1T3G 4M92 5WY8
Enriched GO Terms of Interacting Partners?
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