SMARCB1 - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
KCTD9	potassium channel tetramerization domain containing 9
KLC3	kinesin light chain 3	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
KLF1	Kruppel like factor 1			Congenital dyserythropoietic anemias (CDAs)
KMT2B	lysine methyltransferase 2B	PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
KMT2C	lysine methyltransferase 2C	PKMTs methylate histone lysines Activation of anterior HOX genes in hindbrain development during early embryogenesis RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
KPNA6	karyopherin subunit alpha 6
KRT15	keratin 15	Keratinization Formation of the cornified envelope
KRT19	keratin 19	Keratinization Formation of the cornified envelope
KRT6A	keratin 6A	Keratinization Formation of the cornified envelope	Zinc Zinc acetate	Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
KRT6B	keratin 6B	Keratinization Formation of the cornified envelope		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
KRT6C	keratin 6C	Keratinization Formation of the cornified envelope
LDOC1	LDOC1 regulator of NFKB signaling
LENG8	leukocyte receptor cluster member 8
LNX2	ligand of numb-protein X 2
LY96	lymphocyte antigen 96	ER-Phagosome pathway Caspase activation via Death Receptors in the presence of ligand Toll Like Receptor 4 (TLR4) Cascade MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88-independent TLR4 cascade TRIF-mediated programmed cell death MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) Regulation of TLR by endogenous ligand Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon IKK complex recruitment mediated by RIP1 TRAF6-mediated induction of TAK1 complex within TLR4 complex IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Morphine (R)-3-hydroxytetradecanoic acid Lauric acid Myristic acid
LZTS2	leucine zipper tumor suppressor 2
MAP1LC3B	microtubule associated protein 1 light chain 3 beta	Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
MAP3K20	mitogen-activated protein kinase kinase kinase 20		Dasatinib Fostamatinib
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2
MBIP	MAP3K12 binding inhibitory protein 1	HATs acetylate histones

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