WT1 - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
DVL3	dishevelled segment polarity protein 3	TCF dependent signaling in response to WNT WNT mediated activation of DVL PCP/CE pathway PCP/CE pathway Degradation of DVL Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane Negative regulation of TCF-dependent signaling by DVL-interacting proteins RHO GTPases Activate Formins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
EGR1	early growth response 1	Regulation of PTEN gene transcription Regulation of PTEN gene transcription NGF-stimulated transcription NGF-stimulated transcription Interferon alpha/beta signaling
ETV7	ETS variant transcription factor 7
FAM9B	family with sequence similarity 9 member B
FHL2	four and a half LIM domains 2	PPARA activates gene expression
FMR1NB	FMR1 neighbor
GLIS2	GLIS family zinc finger 2			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GOLGA2	golgin A2	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
HMBOX1	homeobox containing 1
IDI1	isopentenyl-diphosphate delta isomerase 1	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)	Dimethylallyl Diphosphate
IPO8	importin 8	Transcriptional regulation by small RNAs
KLK7	kallikrein related peptidase 7	Degradation of the extracellular matrix	L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide
KPNA4	karyopherin subunit alpha 4	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
KPNA5	karyopherin subunit alpha 5	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
KRT40	keratin 40	Keratinization Formation of the cornified envelope
KRTAP10-1	keratin associated protein 10-1	Keratinization
KRTAP10-3	keratin associated protein 10-3	Keratinization
KRTAP10-4	keratin associated protein 10-4
KRTAP10-5	keratin associated protein 10-5
KRTAP10-6	keratin associated protein 10-6	Keratinization

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