SCO2 and CIDEB

Data Source:
BioGRID (two hybrid)

		SCO2	CIDEB
Description		synthesis of cytochrome C oxidase 2	cell death inducing DFFA like effector b
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Myofibril Integral Component Of Mitochondrial Inner Membrane	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Copper Ion Binding Protein Binding Protein Disulfide Oxidoreductase Activity Copper Chaperone Activity	Protein Binding Identical Protein Binding
	Biological Process	Eye Development In Utero Embryonic Development Muscle System Process Cellular Copper Ion Homeostasis Response To Activity Respiratory Electron Transport Chain Mitochondrial Cytochrome C Oxidase Assembly	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Viral Process Response To Nutrient Levels Bile Acid Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464) Granulocyte percentage of myeloid white cells ( 27863252) Mean corpuscular hemoglobin ( 32888494 20139978) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 21833088) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		2 interacting genes: APP CIDEB	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 C5orf38 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		9997	27141
HPRD ID		05042	11981
Ensembl ID		ENSG00000284194	ENSG00000136305
Uniprot IDs		O43819	Q9UHD4
PDB IDs		2RLI	1D4B
Enriched GO Terms of Interacting Partners?
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