TNFSF15 and PTBP3

Data Source:
BioGRID (affinity chromatography technology)

		TNFSF15	PTBP3
Description		TNF superfamily member 15	polypyrimidine tract binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Nucleus
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding	RNA Binding MRNA Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Tumor Necrosis Factor-mediated Signaling Pathway	MRNA Processing RNA Splicing Anatomical Structure Morphogenesis Negative Regulation Of RNA Splicing Erythrocyte Maturation Regulation Of RNA Splicing Regulation Of Cell Differentiation
Pathways		TNFs bind their physiological receptors
Drugs
Diseases		Crohn's disease
GWAS		Asthma ( 32296059) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 30500874 21102463 32581322 26891255 23266558) Inflammatory bowel disease ( 27569725 18758464 23128233) Leprosy ( 20018961 25642632) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Primary biliary cholangitis ( 28425483 23000144 28062665 30643196) Ulcerative colitis ( 20848476 21297633) Ulcerative colitis or Crohn's disease ( 21699788)	Obstetric antiphospholipid syndrome ( 28424481) Panic disorder ( 31712720)
Interacting Genes		2 interacting genes: TNFRSF25 TNFRSF6B	56 interacting genes: APP MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7C
Entrez ID		9966	9991
HPRD ID		04956	09603
Ensembl ID		ENSG00000181634	ENSG00000119314
Uniprot IDs		A0A0U5JA19 O95150	A0A024R163 O95758
PDB IDs		2O0O 2QE3 2RE9 2RJK 2RJL 3K51 3MI8
Enriched GO Terms of Interacting Partners?
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