MAFB and ZFP64

Data Source:
BioGRID (two hybrid)

		MAFB	ZFP64
Description		MAF bZIP transcription factor B	ZFP64 zinc finger protein
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Segment Specification Sensory Organ Development Respiratory Gaseous Exchange By Respiratory System Rhombomere 5 Development Rhombomere 6 Development Abducens Nerve Formation T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Fat Cell Differentiation Regulation Of Myeloid Cell Differentiation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Thymus Development	Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein B levels ( 32203549) Birth weight ( 31043758 27680694) Bone mineral density (hip) ( 30172743) Cholesterol, total ( 24097068 25961943 20686565) Cleft lip with or without cleft palate ( 28054174) Cognitive decline rate in late mild cognitive impairment ( 26252872) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Dupuytren's disease ( 28886342 21732829) Height ( 25282103) LDL cholesterol ( 24097068 19060906 25961943 20686565) LDL cholesterol levels ( 32203549 28334899) Metabolite levels (lipoprotein measures) ( 27005778) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Obesity-related traits ( 23251661) Orofacial clefts ( 28054174) Paneth cell defects in Crohn's disease ( 28352666) Plasma parathyroid hormone levels ( 30134803) QT interval (ambient particulate matter interaction) ( 28749367) Red blood cell count ( 32888494) Response to TNF antagonist treatment ( 18615156) Serum total protein level ( 29403010) Total body bone mineral density ( 29304378) Triglyceride levels ( 32203549)	Adult body size ( 32376654) Amyotrophic lateral sclerosis ( 17362836) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Parkinson's disease ( 26227905) Reading disability or specific language impairment (pleiotropy) ( 25065397) Subcutaneous adipose tissue ( 22589738) Urinary metabolite levels in chronic kidney disease ( 29545352) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		11 interacting genes: ATF4 BACH1 FOS FOSL1 HOXD12 JUN KRTAP4-2 MAF ZDHHC2 ZFP64 ZWINT	27 interacting genes: AEN BARD1 BEGAIN BYSL EMD ERG28 FAM124A FHL2 L3MBTL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B PRPF31 RBM10 RHOU SETDB1 TAB2 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70
Entrez ID		9935	55734
HPRD ID		07129	15728
Ensembl ID		ENSG00000204103	ENSG00000020256
Uniprot IDs		Q9Y5Q3	B3KQX0 Q9NTW7
PDB IDs			1X5W 2DMD
Enriched GO Terms of Interacting Partners?
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